Vascular complications of diabetes pose a severe threat to human health. Prevention and
treatment protocols based on a single vascular complication are no longer suitable for the …

Peptides are biopolymers, typically consisting of 2–50 amino acids. They are biologically
produced by the cellular ribosomal machinery or by non-ribosomal enzymes and …

Background Microalbuminuria is an early sign of kidney disease in people with diabetes and
indicates increased risk of cardiovascular disease. We tested whether a urinary proteomic …

Diabetic kidney disease (DKD) remains one of the leading causes of reduced lifespan in
diabetes. The quest for both prognostic and surrogate endpoint biomarkers for advanced …

Chronic kidney diseases (CKDs) are currently classified according to their clinical features,
associated comorbidities and pattern of injury on biopsy. Even within a given classification …

Progressive CKD is generally detected at a late stage by a sustained decline in eGFR and/or
the presence of significant albuminuria. With the aim of early and improved risk stratification …

Purpose of review: Diabetic nephropathy (DN) is a progressive kidney disease caused by
alterations in kidney architecture and function, and constitutes one of the leading causes of …

Individuals with diabetes face higher risks for macro-and microvascular complications than
their non-diabetic counterparts. The concept of precision medicine in diabetes aims to …

Capillary electrophoresis combined with mass spectrometry (CE‐MS) has been used for
several years for the investigation of proteins and peptides as biomarkers for diagnosis and …

Background. Chronic kidney disease (CKD) progression is currently assessed by a decline
in estimated glomerular filtration rate (eGFR) and/or an increase in urinary albumin excretion …