The lineage transition between epithelium and mesenchyme is a process known as
epithelial–mesenchymal transition (EMT), by which polarized epithelial cells lose their …

Biological systems display a rich phenomenology of states that resemble the physical states
of matter-solid, liquid and gas. These phases result from the interactions between the …

When animal cells enter mitosis, they round up to become spherical. This shape change is
accompanied by changes in mechanical properties. Multiple studies using different …

During epithelial tissue development, repair, and homeostasis, adherens junctions (AJs)
ensure intercellular adhesion and tissue integrity while allowing for cell and tissue …

The physical state of embryonic tissues emerges from non-equilibrium, collective
interactions among constituent cells. Cellular jamming, rigidity transitions and characteristics …

The collective behaviour of cells in epithelial tissues is dependent on their mechanical
properties. However, the contribution of tissue mechanics to wound healing in vivo remains …

Embryo morphogenesis is impacted by dynamic changes in tissue material properties,
which have been proposed to occur via processes akin to phase transitions (PTs). Here, we …

Mechanical forces are integral to development—from the earliest stages of embryogenesis
to the construction and differentiation of complex organs. Advances in imaging and …

Tissue morphogenesis is driven by local cellular deformations that are powered by
contractile actomyosin networks. How localized forces are transmitted across tissues to …

Tissue morphogenesis is driven by mechanical forces that elicit changes in cell size, shape
and motion. The extent by which forces deform tissues critically depends on the rheological …