DNA microarray technology: devices, systems, and applications

MJ Heller - Annual review of biomedical engineering, 2002 - annualreviews.org
▪ Abstract In this review, recent advances in DNA microarray technology and their
applications are examined. The many varieties of DNA microarray or DNA chip devices and …

Time-resolved fluorescence imaging in biology and medicine

R Cubeddu, D Comelli, C D'Andrea… - Journal of Physics D …, 2002 - iopscience.iop.org
Fluorescence lifetime imaging is a rather new and effective tool that can be used to study
complex biological samples, either at microscopic or macroscopic levels. The map of the …

[图书][B] Principles of fluorescence spectroscopy

JR Lakowicz - 2006 - Springer
The success of fluorescence experiments requires attention to experimental details and an
understanding of the instrumentation. There are also many potential artifacts that can distort …

Functionalization of poly (methyl methacrylate)(PMMA) as a substrate for DNA microarrays

F Fixe, M Dufva, P Telleman… - Nucleic acids …, 2004 - academic.oup.com
A chemical procedure was developed to functionalize poly (methyl methacrylate)(PMMA)
substrates. PMMA is reacted with hexamethylene diamine to yield an aminated surface for …

Time-resolution in fluorometry technologies, labels, and applications in bioanalytical assays

I Hemmilá, VM Mukkala - Critical reviews in clinical laboratory …, 2001 - Taylor & Francis
Time-Resolution in Fluorometry Technologies, Labels, and Applications in Bioanalytical
Assays Page 1 441 Critical Reviews in Clinical Laboratory Sciences, 38(6):441–519 (2001) …

Fabrication of high quality microarrays

M Dufva - Biomolecular engineering, 2005 - Elsevier
Fabrication of DNA microarray demands that between ten (diagnostic microarrays) and
many hundred thousands of probes (research or screening microarrays) are efficiently …

Merging microfluidics with microarray-based bioassays

C Situma, M Hashimoto, SA Soper - Biomolecular engineering, 2006 - Elsevier
Microarray technologies provide powerful tools for biomedical researchers and medicine,
since arrays can be configured to monitor the presence of molecular signatures in a highly …

High-sensitivity detection of DNA hybridization on microarrays using resonance light scattering

P Bao, AG Frutos, C Greef, J Lahiri, U Muller… - Analytical …, 2002 - ACS Publications
The application of resonance light scattering (RLS) particles for high-sensitivity detection of
DNA hybridization on cDNA microarrays is demonstrated. Arrays composed of∼ 2000 …

Improving the signal sensitivity and photostability of DNA hybridizations on microarrays by using dye-doped core− shell silica nanoparticles

X Zhou, J Zhou - Analytical Chemistry, 2004 - ACS Publications
The development of new highly sensitive and selective methods for microarray-based
analysis is a great challenge because, for many bioassays, the amount of genetic material …

Microarrays assembled in microfluidic chips fabricated from poly (methyl methacrylate) for the detection of low-abundant DNA mutations

Y Wang, B Vaidya, HD Farquar, W Stryjewski… - Analytical …, 2003 - ACS Publications
Low-density arrays were assembled into microfluidic channels hot-embossed in poly (methyl
methacrylate)(PMMA) to allow the detection of low-abundant mutations in gene fragments (K …