The human body is home to a complex and diverse microbial ecosystem that plays a central
role in host health. This includes a diversity of fungal species that is collectively referred to …

Initial elimination of invading Staphylococcus aureus from the body is mediated by
professional phagocytes. The neutrophil is the major phagocyte of the innate immunity and …

IgG4, the least represented human IgG subclass in serum, is an intriguing antibody with
unique biological properties, such as the ability to undergo Fab‐arm exchange and limit …

Infections caused by antibiotic-resistant bacteria (ARB) are one of the major global health
challenges of our time. In addition to developing new antibiotics to combat ARB, sensitizing …

Group A streptococcus (GAS) is a major bacterial pathogen responsible for both local and
systemic infections in humans. The molecular mechanisms that contribute to disease …

The activation of Toll-like receptor heterodimer 1/2 (TLR1/2) by microbial components plays
a critical role in host immune responses against pathogens. TLR1/2 signaling is sensitive to …

Upon contact with human plasma, bacteria are rapidly recognized by the complement
system that labels their surface for uptake and clearance by phagocytic cells …

The plasma proteins of the complement system fulfil important immune defence functions,
including opsonization of bacteria for phagocytosis, generation of chemo‐attractants and …

SUMMARY Group A Streptococcus (GAS), also known as Streptococcus pyogenes, is a
clinically well-adapted human pathogen that harbors rich virulence determinants …

Antimicrobial polymers (APs) are the new type of disinfectants, which can be used in some
cases as an alternative to nowadays overused antibiotics. This review presents the most …