Binding and displacement study of gentamicin, 5-fluorouracil, oxytetracycline and rolitetracycline with (BSA: Drug2) complex using spectroscopic and calorimetric …

M Thorve, N Kishore - International Journal of Biological Macromolecules, 2024 - Elsevier
Understanding of energetics of interactions between drug and protein is essential in
pharmacokinetics and pharmacodynamics study. The binding affinity (K) helps in …

[PDF][PDF] Organism-specific differences in the binding of ketoprofen to serum albumin

MP Czub, AJ Stewart, IG Shabalin, W Minor - IUCrJ, 2022 - journals.iucr.org
Serum albumin is a circulatory transport protein that has a highly conserved sequence and
structure across mammalian organisms. Its ligand-binding properties are of importance as …

Biohybrid electrospun membrane for the filtration of ketoprofen drug from water

R Castagna, S Donini, P Colnago, A Serafini… - ACS …, 2019 - ACS Publications
A current challenge in materials science and biotechnology is to express a specific and
controlled functionality on the large interfacial area of a nanostructured material to create …

Insights into the thermodynamics of polymer nanodot–human serum albumin association: a Spectroscopic and calorimetric approach

A Bhattacharya, S Das, TK Mukherjee - Langmuir, 2016 - ACS Publications
With the advent of newer luminescent nanoparticles for bioimaging applications, their
complex interactions with individual biomolecules need to be understood in great detail …

Quercetin influence on thermal denaturation of bovine serum albumin

A Precupas, R Sandu, VT Popa - The Journal of Physical …, 2016 - ACS Publications
The effect of quercetin (QUER) binding on bovine serum albumin (BSA) thermal
denaturation was systematically investigated by means of differential scanning calorimetry …

Mechanistic insights into the interactions of magnetic nanoparticles with bovine serum albumin in presence of surfactants

D Joseph, S Sachar, N Kishore, S Chandra - Colloids and Surfaces B …, 2015 - Elsevier
This work reports the physicochemical parameters and the nature of association between
magnetic nanoparticles and bovine serum albumin (BSA) in presence of cationic and …

Correlating the Properties of Antibiotics with the Energetics of Partitioning in Colloidal Self-Assemblies and the Effect on the Binding of a Released Drug with a Target …

E Judy, N Kishore - Langmuir, 2021 - ACS Publications
The bioavailability of drugs and the monitoring of efficient dosage requires drug delivery
through suitable vehicles. The partitioning characteristics of the drugs in the delivery …

Modulation of the binding affinity of naproxen to bovine serum albumin by conversion of the drug into amino acid ester salts

P Ossowicz, E Janus, J Klebeko, E Światek… - Journal of Molecular …, 2020 - Elsevier
Naproxen (NAP) is one of the most widely prescribed non-steroidal anti-inflammatory drugs.
Novel formulations of NAP aiming at better water-solubility, dosage, and the onset of action …

The analyses of solvent effects on infrared spectra and thermodynamic parameters, Hirshfeld surface, reduced density gradient and molecular docking of ketoprofen …

IB Isik, N Tekin, SG Sagdinc - Journal of Molecular Structure, 2022 - Elsevier
Ketoprofen is one of the propionic acid class of nonsteroidal anti-inflammatory drugs
(NSAIDs). In the present study, the effects of three different solvents (DMSO, benzene and …

Mode of action of betaine on some amino acids and globular proteins: Thermodynamic considerations

AA Thoppil, E Judy, N Kishore - The Journal of Chemical Thermodynamics, 2017 - Elsevier
The interactions of the amino acids glycine, l-alanine, dl-α-amino-n-butyric acid, l-valine, and
l-leucine have been studied based on values of apparent molar volume (V 2, m, ϕ) and …