Neither normal brain function nor the pathological processes involved in neurological
diseases can be adequately understood without knowledge of the release, uptake and …

The gold standard for studies of glutamate–glutamine (GABA) cycling and its connections to
brain biosynthesis from glucose of glutamate and GABA and their subsequent metabolism …

The release of glutamate during brain anoxia or ischaemia triggers the death of neurons,
causing mental or physical handicap. The mechanism of glutamate release is controversial …

The work of Katz and colleagues (Katz, 1969) provided an understanding of the main
modeof neurotransmitter release in the nervous system. Calcium entry into the presynaptic …

Glutamate transport across the plasma membrane of neurons and glia is powered by the
transmembrane electrochemical gradients for sodium, potassium, and pH, but there is …

In the past few decades, the development of chemosensors for neurotransmitters has
emerged as a research area of significant importance, which attracted a tremendous amount …

The neurotoxic properties of glutamate were first demonstrated in 1957 by Lucas and
Newhouse, 1 who showed that systemic administration of glutamate to infant mice caused …

Glutamate is the most abundant neurotransmitter of the central nervous system, as the
majority of neurons use glutamate as neurotransmitter. It is also well known that this …

GLT1 is the major glutamate transporter of the brain and has been thought to be expressed
exclusively in astrocytes. Although excitatory axon terminals take up glutamate, the …

This review is a critical appraisal of the widespread assumption that high extracellular
glutamate, resulting from enhanced pre-synaptic release superimposed on deficient uptake …