Vilsmeier-haack cyclisation as a facile synthetic route to thieno [2, 3-b] quinolines (Part I)

AA Abu-Hashem, AAM Abdelgawad… - Letters in Organic …, 2023 - benthamdirect.com
Quinoline ring system is extensively dispensed in natural products, especially in alkaloids.
Moreover, thieno [2, 3-b] quinolines have vast biological activities, including urea transporter …

Aldo‐X Bifunctional Building Blocks for the Synthesis of Heterocycles

P Ravichandiran, B Lai, Y Gu - The Chemical Record, 2017 - Wiley Online Library
Compounds containing oxygen, nitrogen, or sulfur atoms inside the rings are attracting much
attention and interest due to their biological importance. In recent years, several methods for …

Rational design of 1, 2, 3-triazole hybrid structures as novel anticancer agents: synthesis, biological evaluation and molecular docking studies

A Çot, M Çeşme, S Onur, E Aksakal… - Journal of …, 2023 - Taylor & Francis
New hybrid compounds belonging to the class of 1, 4-disubstituted 1, 2, 3-triazoles were
synthesized. The structural characterization of the synthesized compounds was performed …

Facile Synthesis of 2-Acylthieno[2,3-b]quinolines via Cu-TEMPO-Catalyzed Dehydrogenation, sp2-C–H Functionalization (Nucleophilic Thiolation by S8) of 2 …

C Teja, FR Nawaz Khan - Organic letters, 2020 - ACS Publications
An efficient, solvent-free synthesis of 2-acylthieno [2, 3-b] quinolines is reported from 2-halo-
quinolinyl ketones through Cu-TEMPO catalyzed dehydrogenation, sp2-C–H …

Synthesis biological studies of some new heterocyclic compound derived from 2-chloro-3-formyl quinoline and 4-(benzyl sulfonyl) acetophenone

M Saleh, AI Ayoub… - Egyptian Journal of …, 2020 - ejchem.journals.ekb.eg
A new series of quinoline chalcones have been prepared from condensations of 2-chloro-3-
formyl quinoline (1) with 4-(benzothio) acetophenone (2) and 4-(benzyl sulfonyl) …

Microwave irradiation for the synthesis of quinoline scaffolds: a review

MS Tople, NB Patel, PP Patel - Journal of the Iranian Chemical Society, 2023 - Springer
This review article provides a detailed overview of the microwave-assisted synthesis of
quinoline and its derivatives. Traditional synthetic techniques require the utilisation of costly …

Efficacy of phenyl quinoline phenol derivatives as COX-2 inhibitors; an approach to emergent the small molecules as the anti-inflammatory and analgesic therapeutics

A Manikandan, S Ravichandran… - …, 2017 - Springer
(4-phenylquinoline-2-yl) phenol derivatives (4a-l) with COX-2 enzyme inhibition, analgesic,
anti-inflammatory and antipyretic potentials were executed and reported. From the in vitro …

[HTML][HTML] Solvent-free microwave reactions towards significant organic transformations: A green approach

A Mondal, C Mukhopadhyay - Tetrahedron Green Chem, 2024 - Elsevier
The electromagnetic radiation from microwave irradiation has been widely employed as a
heating source in various significant organic transformations over the past two decades. The …

An ecofriendly synthesis and DNA binding interaction study of some pyrazolo [1, 5-a] pyrimidines derivatives

SS Chobe, BS Dawane, KM Tumbi… - Bioorganic & medicinal …, 2012 - Elsevier
The DNA molecule is a target for plethora of anticancer and antiviral drugs that forms
covalent and non-covalent adducts with major or minor groove of DNA. In present study we …

Synthesis and antibacterial evaluation of 3-acetyl-2H-selenopyrano [2, 3-b] quinolin-2-ones

BP Nandeshwarappa, S Chandrashekharappa… - Chemical Data …, 2020 - Elsevier
In the present study, we have worked out a convenient route for the synthesis of new series
of novel 3-acetyl-2H-selenopyrano [2, 3-b] quinolin-2-ones (4a-f) by the cyclization of 3 …