Translational animal models provide insight into mesenchymal stromal cell (MSC) secretome therapy

RM Harman, C Marx, GR Van de Walle - Frontiers in Cell and …, 2021 - frontiersin.org
The therapeutic potential of the mesenchymal stromal cell (MSC) secretome, consisting of all
molecules secreted by MSCs, is intensively studied. MSCs can be readily isolated …

Immunotherapy in mastitis: state of knowledge, research gaps and way forward

A Saleem, S Saleem Bhat, F A. Omonijo… - Veterinary …, 2024 - Taylor & Francis
Mastitis is an inflammatory condition that affects dairy cow's mammary glands. Traditional
treatment approaches with antibiotics are increasingly leading to challenging scenarios …

Safety and efficacy of a mesenchymal stem cell intramammary therapy in dairy cows with experimentally induced Staphylococcus aureus clinical mastitis

OA Peralta, C Carrasco, C Vieytes, MJ Tamayo… - Scientific reports, 2020 - nature.com
Although, antibiotics are effective in the treatment of bovine mastitis, they do not address the
regeneration of mammary glandular tissue and have been associated to the increment in …

Bovine fetal mesenchymal stem cells obtained from omental adipose tissue and placenta are more resistant to cryoprotectant exposure than those from bone marrow

R Oyarzo, X Valderrama, F Valenzuela… - Frontiers in Veterinary …, 2021 - frontiersin.org
Recent studies have shown promise for the development of cellular therapies with
mesenchymal stem cells (MSCs) in livestock species, specifically bovines, and …

Comparisons of neurotrophic effects of mesenchymal stem cells derived from different tissues on chronic spinal cord injury rats

T Otsuka, Y Maeda, T Kurose, K Nakagawa… - Stem Cells and …, 2021 - liebertpub.com
Cell-based therapies with mesenchymal stem cells (MSCs) are considered as promising
strategies for spinal cord injury (SCI). MSCs have unique characteristics due to differences …

Intrinsic angiogenic potential and migration capacity of human mesenchymal stromal cells derived from menstrual blood and bone marrow

RA Santos, KD Asensi, JHO de Barros… - International Journal of …, 2020 - mdpi.com
Several therapies are being developed to increase blood circulation in ischemic tissues.
Despite bone marrow-derived mesenchymal stromal cells (bmMSC) are still the most …

An update on applications of cattle mesenchymal stromal cells

B Merlo, PM Gugole, E Iacono - Animals, 2022 - mdpi.com
Simple Summary Among livestock species, cattle are crucially important for the meat and
milk production industry. Cows can be affected by different pathologies, such as mastitis …

[HTML][HTML] Expansion of human umbilical cord derived mesenchymal stem cells in regenerative medicine

SN Rajput, BK Naeem, A Ali, A Salim… - World Journal of Stem …, 2024 - ncbi.nlm.nih.gov
BACKGROUND Stem cells are undifferentiated cells that possess the potential for self-
renewal with the capacity to differentiate into multiple lineages. In humans, their limited …

Human liver derived mesenchymal stromal cells ameliorate murine ischemia-induced inflammation through macrophage polarization

Y Liang, E Ozdogan, MJ Hansen, H Tang… - Frontiers in …, 2024 - frontiersin.org
Introduction The immunomodulatory properties of mesenchymal stromal cells (MSC) have
been well-characterized in in-vitro and in-vivo models. We have previously shown that liver …

Single-cell transcriptomics identifies adipose tissue CD271+ progenitors for enhanced angiogenesis in limb ischemia

O Inoue, C Goten, D Hashimuko, K Yamaguchi… - Cell Reports …, 2023 - cell.com
Therapeutic angiogenesis using mesenchymal stem/stromal cell grafts have shown modest
and controversial effects in preventing amputation for patients with critical limb ischemia …