[HTML][HTML] Oxidative stress pathways of air pollution mediated toxicity: Recent insights

RS Gangwar, GH Bevan, R Palanivel, L Das… - Redox biology, 2020 - Elsevier
Ambient air pollution is a leading environmental cause of morbidity and mortality globally
with most of the outcomes of cardiovascular origin. While numerous mechanisms are …

Particulate matter air pollutants and cardiovascular disease: Strategies for intervention

A Aryal, AC Harmon, TR Dugas - Pharmacology & therapeutics, 2021 - Elsevier
Air pollution is consistently linked with elevations in cardiovascular disease (CVD) and CVD-
related mortality. Particulate matter (PM) is a critical factor in air pollution-associated CVD …

Neurotoxicity of fine and ultrafine particulate matter: a comprehensive review using a toxicity pathway-oriented adverse outcome pathway framework

SJ Qin, QG Zeng, HX Zeng, SP Li, J Andersson… - Science of The Total …, 2024 - Elsevier
Abstract Fine particulate matter (PM 2.5) can cause brain damage and diseases. Of note,
ultrafine particles (UFPs) with an aerodynamic diameter less than or equal to 100 nm are a …

[HTML][HTML] The pathophysiological and molecular mechanisms of atmospheric PM2. 5 affecting cardiovascular health: A review

S Feng, F Huang, Y Zhang, Y Feng, Y Zhang… - Ecotoxicology and …, 2023 - Elsevier
Background Exposure to ambient fine particulate matter (PM 2.5, with aerodynamic diameter
less than 2.5 µm) is a leading environmental risk factor for global cardiovascular health …

The underlying mechanism of PM2. 5-induced ischemic stroke

Z Chen, P Liu, X Xia, L Wang, X Li - Environmental Pollution, 2022 - Elsevier
Under the background of global industrialization, PM 2.5 has become the fourth-leading risk
factor for ischemic stroke worldwide, according to the 2019 GBD estimates. This highlights …

Neurotoxicity of the air-borne particles: from molecular events to human diseases

F Liu, C Liu, Y Liu, J Wang, Y Wang, B Yan - Journal of Hazardous Materials, 2023 - Elsevier
Exposure to PM 2.5 is associated with an increased incidence of CNS diseases in humans,
as confirmed by numerous epidemiological studies. Animal models have demonstrated that …

Particulate air pollution exaggerates diet-induced insulin resistance through NLRP3 inflammasome in mice

J Zhong, G Zhao, S Edwards, J Tran… - Environmental …, 2023 - Elsevier
Abstract Air particulate matter 2.5 (PM 2.5) has been demonstrated to exaggerate insulin
resistance in both human and animal studies. However, the exact molecular mechanisms …

Air pollution: another threat to HDL function

A Ossoli, F Cetti, M Gomaraschi - International Journal of Molecular …, 2022 - mdpi.com
Epidemiological studies have consistently demonstrated a positive association between
exposure to air pollutants and the incidence of cardiovascular disease, with the strongest …

The role of the renal dopaminergic system and oxidative stress in the pathogenesis of hypertension

WN Qaddumi, PA Jose - Biomedicines, 2021 - mdpi.com
The kidney is critical in the long-term regulation of blood pressure. Oxidative stress is one of
the many factors that is accountable for the development of hypertension. The five dopamine …

Experimental rodent models exposed to fine particulate matter (PM2. 5) highlighting the injuries in the central nervous system: A systematic review

APS Ferreira, JMO Ramos, GD Gamaro, A Gioda… - Atmospheric Pollution …, 2022 - Elsevier
Exposure to the air pollution represents a major health risk, particulate matter is referred as
harmful component of the environmental contamination. The central nervous system …