Bile acid signaling in inflammatory bowel diseases

S Fiorucci, A Carino, M Baldoni, L Santucci… - Digestive Diseases and …, 2021 - Springer
Bile acids are a group of chemically different steroids generated at the host/microbial
interface. Indeed, while primary bile acids are the end-product of cholesterol breakdown in …

Vitamin D effects on musculoskeletal health, immunity, autoimmunity, cardiovascular disease, cancer, fertility, pregnancy, dementia and mortality—a review of recent …

P Pludowski, MF Holick, S Pilz, CL Wagner… - Autoimmunity …, 2013 - Elsevier
Background Optimal vitamin D intake and its status are important not only for bone and
calcium-phosphate metabolism, but also for overall health and well-being. Vitamin D …

Vitamin D status and outcomes for hospitalised older patients with COVID-19

V Baktash, T Hosack, N Zahari, S Shah… - Postgraduate …, 2021 - academic.oup.com
Purpose Older adults are more likely to be vitamin D deficient. The aim of the study was to
determine whether these patients have worse outcomes with COVID-19. Methods We …

Bile acid metabolites control TH17 and Treg cell differentiation

S Hang, D Paik, L Yao, E Kim, J Trinath, J Lu, S Ha… - Nature, 2019 - nature.com
Bile acids are abundant in the mammalian gut, where they undergo bacteria-mediated
transformation to generate a large pool of bioactive molecules. Although bile acids are …

Vitamin D and multiple sclerosis: An update

C Pierrot-Deseilligny, JC Souberbielle - Multiple sclerosis and related …, 2017 - Elsevier
The most recent findings linking exposure to sun and vitamin D insufficiency to multiple
sclerosis (MS) are reviewed. Due to insufficient sunshine and changing lifestyles …

Vitamin D and the immune system

C Aranow - Journal of investigative medicine, 2011 - journals.sagepub.com
It is now clear that vitamin D has important roles in addition to its classic effects on calcium
and bone homeostasis. As the vitamin D receptor is expressed on immune cells (B cells, T …

Vitamin D: modulator of the immune system

F Baeke, T Takiishi, H Korf, C Gysemans… - Current opinion in …, 2010 - Elsevier
1, 25-dihydroxyvitamin D3 (1, 25 (OH) 2D3), the active form of vitamin D, is known to
regulate calcium and phosphorus metabolism, thus being a key-player in bone-formation …

Impact of vitamin D on immune function: lessons learned from genome-wide analysis

RF Chun, PT Liu, RL Modlin, JS Adams… - Frontiers in …, 2014 - frontiersin.org
Immunomodulatory responses to the active form of vitamin D (1, 25-dihydroxyvitamin D, 1,
25D) have been recognized for many years, but it is only in the last 5 years that the potential …

Vitamin D and the immune system: new perspectives on an old theme

M Hewison - Rheumatic Disease Clinics, 2012 - rheumatic.theclinics.com
Nonclassic actions of vitamin D were first recognized 30 years ago when receptors for active
1, 25-dihydroxyvitamin D3 (1, 25 (OH) 2D3) were detected in various neoplastic cells lines …

Vitamin effects on the immune system: vitamins A and D take centre stage

JR Mora, M Iwata, UH Von Andrian - Nature reviews immunology, 2008 - nature.com
Vitamins are essential constituents of our diet that have long been known to influence the
immune system. Vitamins A and D have received particular attention in recent years as …