Upon entering the biological milieu, nanomedicines swiftly interact with the surrounding
tissue fluid, subsequently being enveloped by a dynamic interplay of biomacromolecules …

Messenger RNA (mRNA) holds great potential in developing immunotherapy, protein
replacement, and genome editing. In general, mRNA does not have the risk of being …

Messenger RNA (mRNA) is the template for protein biosynthesis and is emerging as an
essential active molecule to combat various diseases, including viral infection and cancer …

Abstract mRNA based infectious disease vaccines have opened the venue for development
of novel nucleic acids-based therapeutics. For all mRNA therapeutics dedicated delivery …

Developing safe and effective double-stranded RNA (dsRNA) delivery systems remains a
major challenge for gene silencing, especially in lepidopteran insects. This study evaluated …

Vectorized small interfering RNAs (siRNAs) are widely used to induce gene silencing.
Among the delivery systems used, lipid-based particles are the most effective. Our objective …

Messenger ribonucleic acid (mRNA) vaccines made their successful public debut in the
effort against the COVID‐19 outbreak starting in late 2019, although the history of mRNA …

The coronavirus (COVID-19) pandemic has underscored the critical role of mRNA-based
vaccines as powerful, adaptable, readily manufacturable, and safe methodologies for …

Cancer immunotherapy has gained popularity in recent years in the search for effective
treatment modalities for various malignancies, particularly those that are resistant to …

The increasing number of approved nucleic acid therapeutics demonstrates the potential for
the prevention and treatment of a broad spectrum of diseases. This trend underscores the …