Mitochondria are crucial organelles that play a central role in various cell signaling and
metabolic pathways. A healthy mitochondrial population is maintained through a series of …

Autophagy–the lysosomal degradation of cytoplasm–plays a central role in cellular
homeostasis and protects cells from potentially harmful agents that may accumulate in the …

The actin cytoskeleton impacts practically every function of a eukaryotic cell. Historically, the
best-characterized cytoskeletal activities are in cell morphogenesis, motility, and division …

Autophagy is a cellular process by which proteins and organelles are degraded inside the
lysosome. Exercise is known to influence the regulation of autophagy in skeletal muscle …

Autophagy is a catabolic process in which a double-membrane organelle, the
autophagosome (AP), engulfs cellular components that will be degraded in the lysosomes …

Autophagy is an intracellular degradative process with an important role in cellular
homeostasis. Here, we show that the RNA binding protein (RBP), heterogeneous nuclear …

We report the first structure–activity studies of arylidene–indolinone compound GW5074,
which was reported as a ligand of autophagy-related protein LC3B. The literature has …

Autophagosomes are formed by the enlargement and sealing of phagophores. This is
accompanied by the recruitment and release of autophagy-related (Atg) proteins that …

Retromer prevents the destruction of numerous receptors by recycling them from
endosomes to the trans-Golgi network or plasma membrane. This enables retromer to fine …

Macroautophagy/autophagy, an evolutionarily conserved cellular degradation pathway,
involves phagophores that sequester cytoplasmic constituents and mature into …