Fibroblast growth factors (FGFs) have been implicated in diverse cellular processes
including apoptosis, cell survival, chemotaxis, cell adhesion, migration, differentiation, and …

During development, vertebrate embryos undergo dramatic changes in shape. The
lengthening and narrowing of a field of cells, termed convergent extension, contributes to a …

Prostate cancer is a leading cause of cancer-related death in males and is second only to
lung cancer. Although effective surgical and radiation treatments exist for clinically localized …

Gastrulation in the amphibian embryo is driven by cells of the mesoderm. One of the genes
that confers mesodermal identity in Xenopus is Brachyury (Xbra), which is required for …

The T‐box gene family, encoding related DNA‐binding transcriptional regulators, plays an
essential role in controlling many aspects of embryogenesis in a wide variety of organisms …

The study of planarian regeneration may help us to understand how we can rebuild organs
and tissues after injury, disease or ageing. The robust regenerative abilities of planarians …

In Xenopus, the Mix/Bix family of homeobox genes has been implicated in mesendoderm
development. Mixl1 is the only known murine member of this family. To examine the role of …

▪ Abstract In vertebrates, the paraxial mesoderm corresponds to the bilateral strips of
mesodermal tissue flanking the notochord and neural tube and which are delimited laterally …

Promptly after the notochord domain is specified in the vertebrate dorsal mesoderm, it
undergoes dramatic morphogenesis. Beginning during gastrulation, convergence and …

Gastrulation, the period during the early development of animals when major cell and tissue
movements remodel an initially unstructured group of cells, requires coordinated control of …