Ferroptosis: The entanglement between traditional drugs and nanodrugs in tumor therapy

K Liu, L Huang, S Qi, S Liu, W Xie, L Du… - Advanced …, 2023 - Wiley Online Library
Ferroptosis is a non‐apoptotic programmed cell death caused by the accumulation of lipid
peroxide. System Xc‐/glutathione peroxidase 4 (GPX4) axis and iron axis are two main …

The application of nanoparticles based on ferroptosis in cancer therapy

Y Li, C Wei, J Yan, F Li, B Chen, Y Sun, K Luo… - Journal of Materials …, 2024 - pubs.rsc.org
Ferroptosis is a new form of non-apoptotic programmed cell death. Due to its effectiveness in
cancer treatment, there are increasing studies on the application of nanoparticles based on …

[HTML][HTML] DMT1-dependent endosome-mitochondria interactions regulate mitochondrial iron translocation and metastatic outgrowth

J Barra, I Crosbourne, CL Roberge, R Bossardi-Ramos… - Oncogene, 2024 - nature.com
Transient early endosome (EE)-mitochondria interactions can mediate mitochondrial iron
translocation, but the associated mechanisms are still elusive. We showed that Divalent …

A comparative study of novel ruthenium (III) and iron (III) complexes containing uracil; docking and biological studies

F Althobaiti, HA Sahyon, MMAH Shanab… - Journal of Inorganic …, 2023 - Elsevier
Structural and biological studies were conducted on the novel complexes [Fe (U) 2 (H 2 O)
2] Cl 3 (FeU) and [Ru (U) 2 (H 2 O) 2] Cl 3 (RuU)(U= 5, 6-Diamino-1, 3-dimethylpyrimidine-2 …

Molecular determinants of intrinsic cellular stiffness in health and disease

Z Su, Z Chen, K Ma, H Chen, JWK Ho - Biophysical Reviews, 2022 - Springer
In recent years, the role of intrinsic biophysical features, especially cellular stiffness, in
diverse cellular and disease processes is being increasingly recognized. New high …

[HTML][HTML] Antiproliferative Effect of Inorganic and Organic Selenium Compounds in Breast Cell Lines

NS da Costa, LS Lima, FAM Oliveira, MEA Galiciolli… - Biomedicines, 2023 - mdpi.com
Triple-negative breast cancer (TNBC) is an aggressive, fast-growing tumor that is more likely
to spread to distant organs. Among women diagnosed with breast cancer, the prevalence of …

Fenton-Hydroxyl Radical Antioxidant Efficiency of Ibuprofen-Fe3O4-GO Nanospheres

A Drinevskyi, E Zelkovskyi, V Labunov… - ACS Applied Nano …, 2024 - ACS Publications
A feasible one-step “solvent-antisolvent” oil-free acoustic emulsification method is
demonstrated for the complexation of pristine ibuprofen with Fe3O4-GO in the form of …

Water‐Soluble Fe (II) Complexes for Theranostic Application: Synthesis, Photoacoustic Imaging, and Photothermal Conversion

M Delcroix, A Reddy Marri, S Parant… - European Journal of …, 2023 - Wiley Online Library
Significant effort focused on developing photoactivatable theranostics for localized image
guided therapy of cancer by thermal ablation. In this context iron complexes were recently …