SARS-CoV-2 pathogenesis

MM Lamers, BL Haagmans - Nature reviews microbiology, 2022 - nature.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
caused a devastating pandemic. Although most people infected with SARS-CoV-2 develop …

Viral persistence in children infected with SARS-CoV-2: current evidence and future research strategies

D Buonsenso, L Martino, R Morello, F Mariani… - The Lancet …, 2023 - thelancet.com
Summary In this Personal View, we discuss current knowledge on SARS-CoV-2 RNA or
antigen persistence in children infected with SARS-CoV-2. Based on the evidence that the …

SARS-CoV-2 infection and persistence in the human body and brain at autopsy

SR Stein, SC Ramelli, A Grazioli, JY Chung, M Singh… - Nature, 2022 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) is known to cause multi-organ dysfunction,–
during acute infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

SARS-CoV-2 crosses the blood–brain barrier accompanied with basement membrane disruption without tight junctions alteration

L Zhang, L Zhou, L Bao, J Liu, H Zhu, Q Lv… - Signal transduction and …, 2021 - nature.com
SARS-CoV-2 has been reported to show a capacity for invading the brains of humans and
model animals. However, it remains unclear whether and how SARS-CoV-2 crosses the …

[HTML][HTML] A case series of children with acute hepatitis and human adenovirus infection

LH Gutierrez Sanchez, H Shiau, JM Baker… - … England Journal of …, 2022 - Mass Medical Soc
Background Human adenoviruses typically cause self-limited respiratory, gastrointestinal,
and conjunctival infections in healthy children. In late 2021 and early 2022, several …

The pathogenesis of coronavirus-19 disease

AC Borczuk, RK Yantiss - Journal of biomedical science, 2022 - Springer
Severe acute respiratory syndrome-associated coronavirus-2 (SARS-CoV-2) is the causal
agent of coronavirus disease-2019 (COVID-19), a systemic illness characterized by variably …

Autopsy histopathologic cardiac findings in 2 adolescents following the second COVID-19 vaccine dose

JR Gill, R Tashjian… - Archives of pathology & …, 2022 - meridian.allenpress.com
Context.—Myocarditis in adolescents has been diagnosed clinically following the
administration of the second dose of an mRNA vaccine for coronavirus disease 2019 …

COVID-19 and the vasculature: current aspects and long-term consequences

B Martinez-Salazar, M Holwerda, C Stuedle… - Frontiers in cell and …, 2022 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) was first identified in
December 2019 as a novel respiratory pathogen and is the causative agent of Corona Virus …

[HTML][HTML] COVID-19 vasculopathy: mounting evidence for an indirect mechanism of endothelial injury

RF Nicosia, G Ligresti, N Caporarello, S Akilesh… - The American journal of …, 2021 - Elsevier
Patients with coronavirus disease 2019 (COVID-19) who are critically ill develop vascular
complications characterized by thrombosis of small, medium, and large vessels. Dysfunction …

Complement factor D targeting protects endotheliopathy in organoid and monkey models of COVID-19

E Kawakami, N Saiki, Y Yoneyama, C Moriya… - Cell Stem Cell, 2023 - cell.com
COVID-19 is linked to endotheliopathy and coagulopathy, which can result in multi-organ
failure. The mechanisms causing endothelial damage due to severe acute respiratory …