Objectives To compare the efficacy and safety of antiseizure medications (ASMs), both as
monotherapies and adjunctive therapies, for idiopathic generalized epilepsies (IGEs) and …

Understanding the molecular mechanisms underlying the generation of absence seizures is
crucial for developing effective, patient-specific treatments for childhood absence epilepsy …

Objective This study aims to detect the seizure onset, in childhood absence epilepsy, as
early as possible. Indeed, interfering with absence seizures with sensory simulation has …

Children with epilepsy and identified as responders to antiseizure medications (ASMs) were
found to present markedly higher ghrelin plasma levels when compared to drug-resistant …

Introduction This review aims to identify the optimal therapeutic dosage of anti-epileptic
drugs in terms of efficacy and safety in patients with multiple comorbidities. Areas covered …

The reduced expression of the HCN1 ion channel in the somatosensory cortex (SSC) and
mesolimbic dopamine deficiency are thought to be associated with the genesis of spike …

The mechanisms of epileptogenesis after brain injury, ischemic stroke, or brain tumors have
been extensively studied. As a result, many effective antiseizure drugs have been …

Purpose We tried to differentiate childhood absence epilepsy (CAE) from juvenile absence
epilepsy (JAE) based on their clinical characteristics. We planned to identify a cutoff point for …

Ethosuximide, the first‐line therapy for childhood absence epilepsy, is currently formulated
as a syrup (Zarontin®, Pfizer) with a bitter taste and high sugar content, poorly adapted to …

In this paper, we establish a cortical-thalamic-basal ganglia mean-field computational
network that includes a newly determined direct glutamatergic thalamic-subthalamic …