TRPM channels in human diseases

I Jimenez, Y Prado, F Marchant, C Otero, F Eltit… - Cells, 2020 - mdpi.com
The transient receptor potential melastatin (TRPM) subfamily belongs to the TRP cation
channels family. Since the first cloning of TRPM1 in 1989, tremendous progress has been …

TRPM6 and TRPM7: Novel players in cell intercalation during vertebrate embryonic development

LW Runnels, Y Komiya - Developmental Dynamics, 2020 - Wiley Online Library
A common theme in organogenesis is how the final structure of organs emerge from
epithelial tube structures, with the formation of the neural tube being one of the best …

The kinase activity of the channel-kinase protein TRPM7 regulates stability and localization of the TRPM7 channel in polarized epithelial cells

N Cai, L Lou, N Al-Saadi, S Tetteh… - Journal of Biological …, 2018 - ASBMB
The channel-kinase transient receptor potential melastatin 7 (TRPM7) is a bifunctional
protein with ion channel and kinase domains. The kinase activity of TRPM7 has been linked …

Gene-nutrient interactions that impact magnesium homeostasis increase risk for neural tube defects in mice exposed to dolutegravir

J Gelineau-van Waes, MA van Waes… - Frontiers in Cell and …, 2023 - frontiersin.org
In 2018, data from a surveillance study in Botswana evaluating adverse birth outcomes
raised concerns that women on antiretroviral therapy (ART) containing dolutegravir (DTG) …

Case report: novel TRPM6 mutations cause hereditary hypomagnesemia with secondary hypocalcemia in a Chinese family and a literature Review

Y Han, Y Zhao, H Wang, L Huo - Frontiers in Pediatrics, 2022 - frontiersin.org
Background Hereditary hypomagnesemia with secondary hypocalcemia (HSH) is a rare
autosomal recessive disease due to biallelic TRPM6 mutations. Although the reports of HSH …

Magnesium modulates cellular ROS levels to control cytoskeletal remodeling

N Al-Saadi - 2021 - search.proquest.com
Evidence for putative second messenger functions for Mg 2+ has quietly accumulated for
decades. Bound to DNA, RNA, and ATP and functioning as a cofactor for over 600 different …

[PDF][PDF] Investigating the coordination of thermoregulation by thermosensory mechanisms

HR Malik - 2021 - prism.ucalgary.ca
Thermoregulation is a critical homeostatic process through which organisms maintain
cellular and physiological integrity. Depending on how thermoregulation occurs, organisms …

Širdies Miocitų Magniui Jautrių TRPM6 ir TRPM7 Kanalų Nustatymas ir jų Raiškos Analizė

I Andriulė - 2022 - search.proquest.com
Iki šiol, receptoriaus trumpalaikio atsako į potencialą kanalai (TRP; angl. transient receptor
potential)[1] širdyje detaliau buvo ištirti tik fibroblastuose ir sinusinio mazgo ląstelėse [2] …

[引用][C] 平面细胞极性通路在神经管缺陷中的作用

黄少勇, 蔡润泽, 陈永昌 - 中国比较医学杂志, 2019