Highlights•Chronic stress, depression and inflammation have been consistently
linked.•Stress-induced inflammatory states can contribute to treatment resistance.•Ketamine …

Simple Summary Epigenetics plays a significant role in understanding depression, which is
considered one of the most complex mental health disorders. Epigenetics includes all …

Depression is one of the most common mental disorders. Effects of air pollution from outdoor
and indoor on depression were inconsistent. We assessed 30,139 participants from …

Adverse effects of psychological stress on physical and mental health, especially in older
age, are well documented. How perceived stress relates to the epigenetic clock measure …

Anxiety disorders are common mental health diseases affecting up to 7% of people around
the world. Stress is considered one of the major environmental risk factors to promote …

In this narrative review, we examine biological processes linking psychological stress and
cognition, with a focus on how psychological stress can activate multiple neurobiological …

Major depressive disorder (MDD) is a debilitating psychiatric disorder, the third leading
global cause of disability. Regarding aetiopathogenetic mechanisms involved in the onset of …

Dysregulations of the hypothalamic-pituitary-adrenal (HPA) and sympatho-adrenal
medullary (SAM) axis are associated with mental and somatic illness. However, there is lack …

miRNAs are a class of noncoding RNAs of approximately 19–22 nucleotides that are widely
found in animals, plants, bacteria and even viruses. Dysregulation of the expression profile …

Prenatal excess of glucocorticoids (GCs) is considered to be one of the highly impacting
factors contributing to depression development. Although GCs are crucial for normal fetal …