The role of the androgen receptor (AR) in estrogen receptor (ER)-α-positive breast cancer is
controversial, constraining implementation of AR-directed therapies. Using a diverse …

The field of machine learning has allowed researchers to generate and analyse vast
amounts of data using a wide variety of methodologies. Artificial Neural Networks (ANN) are …

Background Pathological complete response (pCR) is considered a surrogate endpoint for
favorable survival in breast cancer patients treated with neoadjuvant chemotherapy (NAC) …

Sperm-associated Antigen 5 (SPAG5) is a mitotic spindle protein. Recent studies have found
that it is overexpressed in many human cancers and functions as an oncogene. Here, we …

Triple negative breast cancer (TNBC) is an aggressive disease which currently has no
effective therapeutic targets and prominent biomarkers. The Sperm Associated antigen 5 …

Trop2 is considered to have an important function in tumor metastasis and the promotion of
epithelial‑mesenchymal transition (EMT). E‑cadherin is a crucial factor in intercellular …

Multi-gene prognostic signatures of long non-coding RNAs (lncRNAs) provide new insights
into mechanisms of HER2-negative breast cancer development and progression, and …

Background Deregulation of microtubules and centrosome integrity is response for the
initiation and progression of human cancers. Sperm-associated antigen 5 (SPAG5) is …

The emergence of digital immunoassays has advanced the sensitivity of protein analysis to
ultrahigh sensitivity at the attomolar level. However, the background signal generated by the …

Background Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype
that lacks effective therapeutic targets. Sperm-associated antigen 5 (SPAG5) is a mitotic …