Background and Objective: Stroke is a leading cause of morbidity and mortality in both
developed and developing countries all over the world. The only drug for ischemic stroke …

Mitochondrial dysfunction plausibly underlies the aging-associated brain degeneration.
Mitochondria play a pivotal role in cellular bioenergetics and cell-survival. Oxidative stress …

Abstract DL-3-n-Butylphthalide (DL-NBP), a small molecular compound extracted from the
seeds of Apium graveolens Linn (Chinese celery), has been shown to exert neuroprotective …

Pathophysiological processes of stroke have revealed that the damaged brain should be
considered as an integral structure to be protected. However, promising neuroprotective …

Alzheimer's disease (AD) is an age-related, progressive neurodegenerative disorder that
occurs gradually and results in memory, behavior, and personality changes. l-3-n …

Introduction Vascular cognitive impairment without dementia is very common among the
aged and tends to progress to dementia, but there have been no proper large-scale …

Responses to oxidative stress contribute to damage caused by chronic cerebral
hypoperfusion, which is characteristic of certain neurodegenerative diseases. We used a rat …

Chronic cerebral hypoperfusion, induced by permanent occlusion of bilateral common
carotid arteries (2VO), is related to neurological disorders and contributes to cognitive …

目的观察丁苯酞注射液对急性脑梗死患者的有效性和安全性. 方法多中心, 随机, 双盲双模拟,
阳性药物平行对照Ⅲ 期临床研究. 共人组552 例起病48h 内, 美国国立卫生研究院卒中量表 …

In the absence of a cure for Parkinson's disease, development of preventive medications for
this devastating disease is particularly encouraged. Dl-3-n-butylphthalide (NBP), an …