Recent models of Alzheimer's Disease (AD) suggest that neuropathological changes of the
medial temporal lobe, especially entorhinal cortex, are preceded by degenerations of the …

Here we address an important issue that has been embedded within the neuroimaging
community for a long time: the absence of effect estimates in results reporting in the …

Since living in cities is associated with an increased risk for mental disorders such as anxiety
disorders, depression, and schizophrenia, it is essential to understand how exposure to …

Importance Previous in vitro and postmortem research suggests that inflammation may lead
to structural brain changes via activation of microglia and/or astrocytic dysfunction in a range …

Prior studies have highlighted adolescence as a period of increased risk-taking, which is
postulated to result from an overactive reward system in the brain. Longitudinal studies are …

Independent evidence associates β-amyloid pathology with both non-rapid eye movement
(NREM) sleep disruption and memory impairment in older adults. However, whether the …

Childhood poverty has pervasive negative physical and psychological health sequelae in
adulthood. Exposure to chronic stressors may be one underlying mechanism for childhood …

The mesostriatal dopamine system is prominently implicated in model-free reinforcement
learning, with fMRI BOLD signals in ventral striatum notably covarying with model-free …

Therapeutic interventions that incorporate training in mindfulness meditation have become
increasingly popular, but to date, little is known about neural mechanisms associated with …

Importance Converging evidence suggests that Alzheimer disease (AD) involves insulin
signaling impairment. Patients with AD and individuals at risk for AD show reduced glucose …