Antimicrobial resistance and its spread is a global threat

MM Aljeldah - Antibiotics, 2022 - mdpi.com
Antimicrobial resistance (AMR) is a challenge to human wellbeing the world over and is one
of the more serious public health concerns. AMR has the potential to emerge as a serious …

Immunoinformatics and vaccine development: an overview

AN Oli, WO Obialor, MO Ifeanyichukwu… - ImmunoTargets and …, 2020 - Taylor & Francis
The use of vaccines have resulted in a remarkable improvement in global health. It has
saved several lives, reduced treatment costs and raised the quality of animal and human …

Whole genome sequencing and metagenomics for outbreak investigation, source attribution and risk assessment of food‐borne microorganisms

EFSA Panel on Biological Hazards (EFSA … - EFSA …, 2019 - Wiley Online Library
This Opinion considers the application of whole genome sequencing (WGS) and
metagenomics for outbreak investigation, source attribution and risk assessment of food …

The Avian Pathogenic Escherichia coli (APEC) pathotype is comprised of multiple distinct, independent genotypes

JW Mehat, AHM van Vliet, RM La Ragione - Avian Pathology, 2021 - Taylor & Francis
ABSTRACT Avian Pathogenic E. coli (APEC) is the causative agent of avian colibacillosis,
resulting in economic losses to the poultry industry through morbidity, mortality and carcass …

Exploiting genomics for antimicrobial resistance surveillance at One Health interfaces

DM Muloi, E Jauneikaite, MF Anjum, SY Essack… - The Lancet …, 2023 - thelancet.com
The intersection of human, animal, and ecosystem health at One Health interfaces is
recognised as being of key importance in the evolution and spread of antimicrobial …

Defining genomic epidemiology thresholds for common-source bacterial outbreaks: a modelling study

A Duval, L Opatowski, S Brisse - The Lancet Microbe, 2023 - thelancet.com
Background Epidemiological surveillance relies on microbial strain typing, which defines
genomic relatedness among isolates to identify case clusters and their potential sources …

Farm animals and aquaculture: significant reservoirs of mobile colistin resistance genes

Y Shen, R Zhang, S Schwarz, C Wu… - Environmental …, 2020 - Wiley Online Library
Colistin resistance has attracted substantial attention after colistin was considered as a last‐
resort drug for the treatment of infections caused by carbapenem‐resistant and/or multidrug …

Strengthening antimicrobial resistance surveillance systems: a scoping review

PC Do, YA Assefa, SM Batikawai, SA Reid - BMC Infectious Diseases, 2023 - Springer
Background Antimicrobial resistance (AMR) is an emerging global public health crisis.
Surveillance is a fundamental component in the monitoring and evaluation of AMR …

Whole-genome sequencing as part of national and international surveillance programmes for antimicrobial resistance: a roadmap

NIHR Global Health Research Unit on Genomic … - BMJ Global …, 2020 - gh.bmj.com
The global spread of antimicrobial resistance (AMR) and lack of novel alternative treatments
have been declared a global public health emergency by WHO. The greatest impact of AMR …

Exploiting genomics to mitigate the public health impact of antimicrobial resistance

C Waddington, ME Carey, CJ Boinett, E Higginson… - Genome medicine, 2022 - Springer
Antimicrobial resistance (AMR) is a major global public health threat, which has been largely
driven by the excessive use of antimicrobials. Control measures are urgently needed to slow …