Unraveling the journey of cancer stem cells from origin to metastasis
Cancer biology research over recent decades has given ample evidence for the existence of
self-renewing and drug-resistant populations within heterogeneous tumors, widely …
self-renewing and drug-resistant populations within heterogeneous tumors, widely …
[PDF][PDF] The role of cancer stem cells in relapse of solid tumors
[Frontiers in Bioscience E4, 1528-1541, January 1, 2012] 1528 The role of cancer stem cells in
relapse of solid tumors Yang Yu1 Page 1 [Frontiers in Bioscience E4, 1528-1541, January 1 …
relapse of solid tumors Yang Yu1 Page 1 [Frontiers in Bioscience E4, 1528-1541, January 1 …
Negative enrichment by immunomagnetic nanobeads for unbiased characterization of circulating tumor cells from peripheral blood of cancer patients
Z Liu, A Fusi, E Klopocki, A Schmittel, I Tinhofer… - Journal of translational …, 2011 - Springer
Background A limitation of positive selection strategies to enrich for circulating tumor cells
(CTCs) is that there might be CTCs with insufficient expression of the surface target marker …
(CTCs) is that there might be CTCs with insufficient expression of the surface target marker …
Cancer stem cells: an insight into the development of metastatic tumors and therapy resistance
The term “cancer stem cells”(CSCs) refers to cancer cells that exhibit traits parallel to normal
stem cells, namely the potential to give rise to every type of cell identified in a tumor …
stem cells, namely the potential to give rise to every type of cell identified in a tumor …
Role of the HGF/c-MET tyrosine kinase inhibitors in metastasic melanoma
L Demkova, L Kucerova - Molecular cancer, 2018 - Springer
Metastatic disease in a cancer patient still remains a therapeutic challenge. Metastatic
process involves many steps, during which malignant cells succeed to activate cellular …
process involves many steps, during which malignant cells succeed to activate cellular …
Liquid biopsy in melanoma: significance in diagnostics, prediction and treatment monitoring
Liquid biopsy is a common term referring to circulating tumor cells and other biomarkers,
such as circulating tumor DNA (ctDNA) or extracellular vesicles. Liquid biopsy presents a …
such as circulating tumor DNA (ctDNA) or extracellular vesicles. Liquid biopsy presents a …
Therapeutic implications of cellular and molecular biology of cancer stem cells in melanoma
Melanoma is a form of cancer that initiates in melanocytes. Melanoma has multiple
phenotypically distinct subpopulation of cells, some of them have embryonic like plasticity …
phenotypically distinct subpopulation of cells, some of them have embryonic like plasticity …
[HTML][HTML] Circulating tumour cells as tumour biomarkers in melanoma: detection methods and clinical relevance
Circulating tumour cells (CTCs) are cells of solid tumour origin detectable in the peripheral
blood. Their occurrence is considered a prerequisite step for establishing distant …
blood. Their occurrence is considered a prerequisite step for establishing distant …
Desmoplastic melanoma: an updated immunohistochemical analysis of 40 cases with a proposal for an additional panel of stains for diagnosis
JA Plaza, P Bonneau, V Prieto… - Journal of cutaneous …, 2016 - Wiley Online Library
Desmoplastic melanoma (DM) is histologically characterized by a proliferation of spindle
melanocytes dispersed in a collagenous stroma that can be mistaken for a variety of …
melanocytes dispersed in a collagenous stroma that can be mistaken for a variety of …
[HTML][HTML] Melanoma circulating tumor cells: Benefits and challenges required for clinical application
The implementation of novel therapeutic interventions has improved the survival rates of
melanoma patients with metastatic disease. Nonetheless, only 33% of treated cases exhibit …
melanoma patients with metastatic disease. Nonetheless, only 33% of treated cases exhibit …