Gold nanoparticles: emerging paradigm for targeted drug delivery system

A Kumar, X Zhang, XJ Liang - Biotechnology advances, 2013 - Elsevier
The application of nanotechnology in medicine, known as nanomedicine, has introduced a
plethora of nanoparticles of variable chemistry and design considerations for cancer …

Delivery of nanoparticle-based radiosensitizers for radiotherapy applications

F Boateng, W Ngwa - International journal of molecular sciences, 2019 - mdpi.com
Nanoparticle-based radiosensitization of cancerous cells is evolving as a favorable modality
for enhancing radiotherapeutic ratio, and as an effective tool for increasing the outcome of …

Selective targeting of brain tumors with gold nanoparticle-induced radiosensitization

DY Joh, L Sun, M Stangl, A Al Zaki, S Murty… - PloS one, 2013 - journals.plos.org
Successful treatment of brain tumors such as glioblastoma multiforme (GBM) is limited in
large part by the cumulative dose of Radiation Therapy (RT) that can be safely given and the …

Radiosensitization by gold nanoparticles: Will they ever make it to the clinic?

L Cui, S Her, GR Borst, RG Bristow, DA Jaffray… - Radiotherapy and …, 2017 - Elsevier
The utilization of gold nanoparticles (AuNPs) as radiosensitizers has shown great promise in
pre-clinical research. In the current review, the physical, chemical, and biological pathways …

Targeted radiotherapy with gold nanoparticles: current status and future perspectives

W Ngwa, R Kumar, S Sridhar, H Korideck… - …, 2014 - Taylor & Francis
Radiation therapy (RT) is the treatment of cancer and other diseases with ionizing radiation.
The ultimate goal of RT is to destroy all the disease cells while sparing healthy tissue …

Nanoparticle location and material-dependent dose enhancement in X-ray radiation therapy

M Hossain, M Su - The Journal of Physical Chemistry C, 2012 - ACS Publications
Nanoparticles of high atomic number (Z) materials can act as radiosensitizers to enhance
radiation dose delivered to tumors. An analytical approach is used to calculate dose …

Gold nanoparticles in radiotherapy and recent progress in nanobrachytherapy

M Laprise‐Pelletier, T Simão… - Advanced healthcare …, 2018 - Wiley Online Library
Over the last few decades, gold nanoparticles (GNPs) have emerged as “radiosensitizers” in
oncology. Radiosensitizers are additives that can enhance the effects of radiation on …

Gold nanoparticles and their alternatives for radiation therapy enhancement

DR Cooper, D Bekah, JL Nadeau - Frontiers in chemistry, 2014 - frontiersin.org
Radiation therapy is one of the most commonly used treatments for cancer. The dose of
delivered ionizing radiation can be amplified by the presence of high-Z materials via an …

Intratumoral Biosynthesis of Gold Nanoclusters by Pancreatic Cancer to Overcome Delivery Barriers to Radiosensitization

AS Schwartz-Duval, Y Mackeyev, I Mahmud… - ACS …, 2024 - ACS Publications
Nanoparticle delivery to solid tumors is a prime challenge in nanomedicine. Here, we
approach this challenge through the lens of biogeochemistry, the field that studies the flow of …

[HTML][HTML] Gold nanoparticles meet medical radionuclides

N Daems, C Michiels, S Lucas, S Baatout… - Nuclear Medicine and …, 2021 - Elsevier
Thanks to their unique optical and physicochemical properties, gold nanoparticles have
gained increased interest as radiosensitizing, photothermal therapy and optical imaging …