Microvilli are finger-like membrane protrusions, supported by the actin cytoskeleton, and
found on almost all cell types. A growing body of evidence suggests that the dynamic …

The endoplasmic reticulum (ER) undergoes continuous remodelling via a selective
autophagy pathway, known as ER-phagy. ER-phagy receptors have a central role in this …

Membrane-shaping proteins characterized by reticulon homology domains play an
important part in the dynamic remodelling of the endoplasmic reticulum (ER). An example of …

Protein‐based polymers possess chemically defined sequences that can encode diverse
properties and functions into a new class of biopolymeric materials. However, sequence …

Adenomatous polyposis coli (APC) is an important tumor suppressor and is mostly linked to
the regulation of the Wnt/β-catenin signaling pathway. APC mutation has been identified as …

The latest meta-analysis of genome-wide association studies identified 90 independent
variants across 78 genomic regions associated with Parkinson's disease, yet the …

Membrane-shaping proteins are driving forces behind establishment of proper cell
morphology and function. Yet, their reported structural and in vitro properties are noticeably …

With the onset of resistance, ovarian cancer cells display almost unpredictable adaptive
potential. This may derive from the tumor genetic ancestry and can be additionally tailored …

Synaptic plasticity involves proper establishment and rearrangement of structural and
functional microdomains. Yet, visualization of the underlying lipid cues proved challenging …

Cells sense and respond to various mechanical forces from the extracellular matrix primarily
by modulating the actin cytoskeleton. Mechanical forces can be translated into biochemical …