Neuroinflammation: the role and consequences

M Lyman, DG Lloyd, X Ji, MP Vizcaychipi, D Ma - Neuroscience research, 2014 - Elsevier
Neuroinflammation is central to the common pathology of several acute and chronic brain
diseases. This review examines the consequences of excessive and prolonged …

Delirium in elderly adults: diagnosis, prevention and treatment

TG Fong, SR Tulebaev, SK Inouye - Nature Reviews Neurology, 2009 - nature.com
Delirium is a common and serious acute neuropsychiatric syndrome with core features of
inattention and global cognitive dysfunction. The etiologies of delirium are diverse and …

[HTML][HTML] Inflammatory markers in postoperative delirium (POD) and cognitive dysfunction (POCD): a meta-analysis of observational studies

X Liu, Y Yu, S Zhu - PloS one, 2018 - journals.plos.org
Background The aim of this study was to summarize and discuss the similarities and
differences in inflammatory biomarkers in postoperative delirium (POD) and cognitive …

Postoperative delirium and cognitive dysfunction

S Deiner, JH Silverstein - British journal of anaesthesia, 2009 - academic.oup.com
Postoperative delirium and cognitive dysfunction (POCD) are topics of special importance in
the geriatric surgical population. They are separate entities, whose relationship has yet to be …

Early delirium after cardiac surgery: an analysis of incidence and risk factors in elderly (≥ 65 years) and very elderly (≥ 80 years) patients

K Kotfis, A Szylińska, M Listewnik… - … interventions in aging, 2018 - Taylor & Francis
Introduction Postoperative delirium is a common complication of cardiac surgery associated
with increased mortality, morbidity, and long-term cognitive dysfunction. The aim of this study …

ELISA and multiplex technologies for cytokine measurement in inflammation and aging research

SX Leng, JE McElhaney, JD Walston… - The Journals of …, 2008 - academic.oup.com
Over the last decade there has been an enormous expansion of research focused on
defining the role of inflammation in aging, age-related diseases, disability, and frailty. The …

[HTML][HTML] Biomarkers of postoperative delirium and cognitive dysfunction

A Fournier, R Krause, G Winterer… - Frontiers in aging …, 2015 - frontiersin.org
Elderly surgical patients frequently experience postoperative delirium (POD) and the
subsequent development of postoperative cognitive dysfunction (POCD). Clinical features …

Pharmacological interventions for the treatment of delirium in critically ill adults

L Burry, B Hutton, DR Williamson… - Cochrane Database …, 2019 - cochranelibrary.com
Background Although delirium is typically an acute reversible cognitive impairment, its
presence is associated with devastating impact on both short‐term and long‐term outcomes …

Selective anesthesia-induced neuroinflammation in developing mouse brain and cognitive impairment

X Shen, Y Dong, Z Xu, H Wang, C Miao… - The Journal of the …, 2013 - pubs.asahq.org
Background: Recent population studies have suggested that children with multiple
exposures to anesthesia and surgery at an early age are at an increased risk of cognitive …

Pathoetiological model of delirium: a comprehensive understanding of the neurobiology of delirium and an evidence-based approach to prevention and treatment

JR Maldonado - Critical care clinics, 2008 - Elsevier
Delirium is the most common complication found in the general hospital setting. Yet, we
know relatively little about its actual pathophysiology. This article contains a summary of …