Ischemic retinal vein occlusion: characterizing the more severe spectrum of retinal vein occlusion

M Khayat, M Williams, N Lois - Survey of ophthalmology, 2018 - Elsevier
Retinal vein occlusion (RVO)-including central RVO, branch RVO, and hemicentral and
hemispheric RVO—is the second most common vascular cause of visual loss, surpassed …

The role of IL-6-174 G/C polymorphism and intraocular IL-6 levels in the pathogenesis of ocular diseases: a systematic review and meta-analysis

ZS Ulhaq, GV Soraya, Budu, LR Wulandari - Scientific reports, 2020 - nature.com
Abstract Interleukin-6 (IL-6) is one of the key regulators behind the inflammatory and
pathological process associated with ophthalmic diseases. The role of IL-6-174 G/C …

Microglia activation and recruitment of circulating macrophages during ischemic experimental branch retinal vein occlusion

A Ebneter, D Kokona, N Schneider… - … & visual science, 2017 - iovs.arvojournals.org
Purpose: To characterize retinal microglia activation and macrophage recruitment in
experimental branch retinal vein occlusion (BRVO). Methods: Experimental BRVO was …

Advanced glycation endproducts link inflammatory cues to upregulation of galectin-1 in diabetic retinopathy

A Kanda, Y Dong, K Noda, W Saito, S Ishida - Scientific reports, 2017 - nature.com
Diabetic retinopathy (DR) is an inflammatory and progressive vaso-occlusive disease
resulting in angiogenesis. Galectin-1 is a hypoxia-induced angiogenic factor associated with …

Proteomic profiling of plasma biomarkers in acute ischemic stroke due to large vessel occlusion

C Qin, XL Zhao, XT Ma, LQ Zhou, L Wu… - Journal of translational …, 2019 - Springer
Background Acute ischemic stroke (AIS) due to large vessel occlusion (LVO) is a
devastating cerebrovascular disorder, which could benefit from collateral circulation …

[HTML][HTML] Comprehensive analysis of vitreous chemokines involved in ischemic retinal vein occlusion

Y Zeng, D Cao, H Yu, X Zhuang, D Yang, Y Hu… - Molecular …, 2019 - ncbi.nlm.nih.gov
Methods The vitreous humor was collected at the start of 23-gauge pars plana vitrectomy
from patients with ischemic RVO and patients with idiopathic preretinal membranes (PRMs) …

Inhibition of inflammatory cells delays retinal degeneration in experimental retinal vein occlusion in mice

J Jovanovic, X Liu, D Kokona, MS Zinkernagel… - Glia, 2020 - Wiley Online Library
The role of microglia in retinal inflammation is still ambiguous. Branch retinal vein occlusion
initiates an inflammatory response whereby resident microglia cells are activated. They …

FoxP3 expression by retinal pigment epithelial cells: Transcription factor with potential relevance for the pathology of age-related macular degeneration

AS Alfaar, L Stürzbecher, M Diedrichs-Möhring… - Journal of …, 2022 - Springer
Abstract Background Forkhead-Box-Protein P3 (FoxP3) is a transcription factor and marker
of regulatory T cells, converting naive T cells into Tregs that can downregulate the effector …

Neurovascular injury associated non-apoptotic endothelial caspase-9 and astroglial caspase-9 mediate inflammation and contrast sensitivity decline

C Colón Ortiz, AM Neal, MI Avrutsky, M Choi… - Cell Death & …, 2022 - nature.com
Retinal neurovascular injuries are a leading cause of vision loss in young adults presenting
unmet therapeutic needs. Neurovascular injuries damage homeostatic communication …

Sec62 promotes pro-angiogenesis of hepatocellular carcinoma cells under hypoxia

Y Meng, H Zhao, Z Zhao, Z Yin, Z Chen… - Cell biochemistry and …, 2021 - Springer
This study aimed to investigate the underlying molecular pathogenic mechanism of Sec62 in
hepatocellular carcinoma (HCC). Microarray analysis was conducted to profile the global …