The membrane-associated MARCH E3 ligase family: emerging roles in immune regulation
H Lin, S Li, HB Shu - Frontiers in Immunology, 2019 - frontiersin.org
The membrane-associated RING-CH-type finger (MARCH) proteins of E3 ubiquitin ligases
have emerged as critical regulators of immune responses. MARCH proteins target immune …
have emerged as critical regulators of immune responses. MARCH proteins target immune …
[HTML][HTML] BAP31: Physiological functions and roles in disease
EM Quistgaard - Biochimie, 2021 - Elsevier
B-cell receptor-associated protein 31 (BAP31 or BCAP31) is a ubiquitously expressed
transmembrane protein found mainly in the endoplasmic reticulum (ER), including in …
transmembrane protein found mainly in the endoplasmic reticulum (ER), including in …
MARCH8 inhibits influenza A virus infection by targeting viral M2 protein for ubiquitination-dependent degradation in lysosomes
X Liu, F Xu, L Ren, F Zhao, Y Huang, L Wei… - Nature …, 2021 - nature.com
The membrane-associated RING-CH (MARCH) proteins are E3 ligases that regulate the
stability of various cellular membrane proteins. MARCH8 has been reported to inhibit the …
stability of various cellular membrane proteins. MARCH8 has been reported to inhibit the …
MARCH8 inhibits HIV-1 infection by reducing virion incorporation of envelope glycoproteins
Abstract Membrane-associated RING-CH 8 (MARCH8) is one of 11 members of the recently
discovered MARCH family of RING (really interesting new gene)-finger E3 ubiquitin ligases …
discovered MARCH family of RING (really interesting new gene)-finger E3 ubiquitin ligases …
BAP31 regulates the expression of ICAM-1/VCAM-1 via MyD88/NF-κB pathway in acute lung injury mice model
G Li, X Jiang, X Liang, Y Hou, J Zang, B Zhu, C Jia… - Life Sciences, 2023 - Elsevier
Aims The cell adhesion molecules (CAMs) that mediate neutrophil-endothelium cell
adhesion are deeply involved in the pathogenesis of acute lung injury (ALI). B-cell receptor …
adhesion are deeply involved in the pathogenesis of acute lung injury (ALI). B-cell receptor …
Machine learning-assisted elucidation of CD81–CD44 interactions in promoting cancer stemness and extracellular vesicle integrity
Tumor-initiating cells with reprogramming plasticity or stem-progenitor cell properties
(stemness) are thought to be essential for cancer development and metastatic regeneration …
(stemness) are thought to be essential for cancer development and metastatic regeneration …
MARCH ubiquitin ligases alter the itinerary of clathrin-independent cargo from recycling to degradation
CA Eyster, NB Cole, S Petersen… - Molecular biology of …, 2011 - Am Soc Cell Biol
Following endocytosis, internalized plasma membrane proteins can be recycled back to the
cell surface or trafficked to late endosomes/lysosomes for degradation. Here we report on …
cell surface or trafficked to late endosomes/lysosomes for degradation. Here we report on …
MARCH1 regulates insulin sensitivity by controlling cell surface insulin receptor levels
A Nagarajan, MC Petersen, AR Nasiri, G Butrico… - Nature …, 2016 - nature.com
Insulin resistance is a key driver of type 2 diabetes (T2D) and is characterized by defective
insulin receptor (INSR) signalling. Although surface INSR downregulation is a well …
insulin receptor (INSR) signalling. Although surface INSR downregulation is a well …
Advances in HIV-1 assembly
G Lerner, N Weaver, B Anokhin, P Spearman - Viruses, 2022 - mdpi.com
The assembly of HIV-1 particles is a concerted and dynamic process that takes place on the
plasma membrane of infected cells. An abundance of recent discoveries has advanced our …
plasma membrane of infected cells. An abundance of recent discoveries has advanced our …
Overview of the membrane-associated RING-CH (MARCH) E3 ligase family
E3 ligases are critical checkpoints for protein ubiquitination, a signal that often results in
protein sorting and degradation but has also been linked to regulation of transcription and …
protein sorting and degradation but has also been linked to regulation of transcription and …