The spermatozoon is a highly differentiated and polarized cell, with two main structures: the
head, containing a haploid nucleus and the acrosomal exocytotic granule, and the flagellum …

Small non-coding RNAs (sncRNAs), being the top regulators of gene expression, have been
thoroughly studied in various biological systems, including the testis. Research over the last …

During human spermatogenesis, germ cells undergo dynamic changes in chromatin
organization/re-packaging and in transcriptomes. In order to better understand the …

Recent developments in stem cell technologies have made significant advancements in the
field of in vitro gametogenesis. In vitro gametogenesis (IVG) is a promising technology …

Background Lymphocyte antigen 6 complex, locus K (LY6K) is a putative oncogene in
various cancers. Elevated expression of LY6K is correlated with poor patient prognosis in …

Gene expression during spermatogenesis undergoes significant changes due to a
demanding sequence of mitosis, meiosis, and differentiation. We investigated the …

The generation of spermatozoa from developing germ cells through mitotic and meiotic
divisions is a highly regulated and complex process. Any defect in this process, may lead to …

Litter size and teat number are economically important traits in the porcine industry.
However, the genetic mechanisms influencing these traits remain unknown. In this study, we …

Spermatogenesis is tightly controlled at transcriptional, post-transcriptional, and epigenetic
levels by various regulators, including miRNAs. This study deals with the identification of …

Spermatogenesis relies on complex molecular mechanisms, essential for the genesis and
differentiation of the male gamete. Germ cell differentiation starts at the testicular …