Background and Objectives: Several polymorphisms have been described in various DNA
repair genes. Nucleotide excision DNA repair (NER) detects defects of DNA molecules and …

Background Xeroderma pigmentosum complementation group C (XPC), a DNA repair
protein, plays an important role in the maintenance of genomic integrity and is essential for …

As per the Global Cancer Observatory, the WHO Eastern Mediterranean region (which
includes the Arabic countries) ranks highest for age-standardized mortality rate at 4 per …

The impact of physical activity on the levels of genomic damage is still poorly understood. In
this work, we aimed to investigate the influence of a constant martial arts training on the …

Background There is mounting evidence that the genotypes of DNA repair proteins and
susceptibility to certain malignancies are related. Few studies, however, have examined the …

Background Genetic alterations of the DNA repair genes might decrease the efficiency of
DNA repair mechanisms and increase susceptibility to cancers such as acute myeloid …

Purpose-The influence of training on the levels of genomic damage are not univocal, and to
date not completely understood. Indeed, studies in this area remain scant and do not draw …

Xeroderma pigmentosum (XP) is an autosomal recessive disorder caused by defect in
nucleotide excision repair and is associated with increased incidence of skin cancer …

Background: The effects of single nucleotide polymorphisms (SNPs) at nucleotide excision
repair (NER) pathway on susceptibility to cutaneous melanoma (CM) are of great interest. To …