Infectious diseases are the leading cause of mortality worldwide, with viruses in particular
making global impact on healthcare and socioeconomic development. In addition, the rapid …

Abstract Design and synthesis of efficient drug delivery systems are of vital importance for
medicine and healthcare. Nanocarrier-based drug delivery systems, in particular …

Immunotherapy is an emerging treatment option for use following traditional cancer
treatments (surgical resection, radiotherapy and chemotherapy). Due to the complexity of the …

The immunosuppressive state of the tumor microenvironment diminishes the efficacy of
dendritic cell (DC)-based cancer immunotherapy. Inhibitory immune checkpoint molecules …

The immunosuppressive factors in tumor microenvironment enhance tumor growth and
suppress anti-tumor immune responses. Adenosine is an important immunosuppressive …

Cancer is one of the leading causes of death and mortality in the world. There is an essential
need to develop new drugs or therapeutic approaches to manage treatment-resistant …

: Vaccination has had great success in history of medicine with both infectious and non-
infectious diseases listed in the realm of vaccines. The significant decrease in deaths from …

MicroRNAs (miRNAs) have emerged as a class of regulatory RNAs in host–pathogen
interactions. Aberrant miRNA expression seems to play a central role in the pathology of …

Abnormal expression of several macromolecules within tumor milieu helps the development
of neoplasia and immune suppression in various cancers. ZEB-1 and CD73 are important …

Background Cervical cancer is the second-most-common cause of malignancies in women
worldwide, and the oncogenic activity of the human papilloma virus types (HPV) E7 protein …