Single-molecule localization microscopy (SMLM) is a relatively new imaging modality,
winning the 2014 Nobel Prize in Chemistry, and considered as one of the key super …

Super-resolution fluorescence microscopy allows the investigation of cellular structures at
nanoscale resolution using light. Current developments in super-resolution microscopy have …

Motivation Localization microscopy data is represented by a set of spatial coordinates, each
corresponding to a single detection, that form a point cloud. This can be analyzed either by …

摘要21 世纪初诞生的超分辨光学成像技术凭借纳米级空间分辨率, 低损制样等优点,
迅速发展成为生命科学研究中不可或缺的技术手段. 其中单分子定位超分辨成像(SMLM) …

Quantitative approaches to analyze the large data sets generated by single molecule
localization super-resolution microscopy (SMLM) are limited. We developed a computational …

Immune synapse (IS) formation by T lymphocytes constitutes a crucial event involved in
antigen-specific, cellular and humoral immune responses. After IS formation by T …

It has been two decades since the lipid raft hypothesis was first presented. Even today,
whether these nanoscale cholesterol-rich domains are present in cell membranes is not …

Abstract v LUME is a virtual reality software package designed to render large three-
dimensional single-molecule localization microscopy datasets. v LUME features include …

Blinking nanoscale emitters, typically single molecules, are employed in single‐molecule
localization microscopy (SMLM), such as direct stochastic optical reconstruction microscopy …

The interactions between and with nanostructures can only be fully understood when the
functional group distribution on their surfaces can be quantified accurately. Here we apply a …