Obesity and cancer risk: Emerging biological mechanisms and perspectives

KI Avgerinos, N Spyrou, CS Mantzoros, M Dalamaga - Metabolism, 2019 - Elsevier
Continuously rising trends in obesity-related malignancies render this disease spectrum a
public health priority. Worldwide, the burden of cancer attributable to obesity, expressed as …

Gut microbiota-mediated inflammation in obesity: a link with gastrointestinal cancer

PD Cani, BF Jordan - Nature Reviews Gastroenterology & Hepatology, 2018 - nature.com
Overweight and obesity are associated with increased risk of developing metabolic
disorders such as diabetes and cardiovascular diseases. However, besides these metabolic …

[HTML][HTML] Inflammation and cancer: paradoxical roles in tumorigenesis and implications in immunotherapies

X Liu, L Yin, S Shen, Y Hou - Genes & Diseases, 2023 - Elsevier
Chronic inflammation caused by persistent infections and metabolic disorders is thought to
contribute to the increased cancer risk and the accelerated cancer progression. Oppositely …

Colon cancer: inflammation associated cancer

S Shawki, J Ashburn, SA Signs… - … Oncology Clinics of …, 2017 - pmc.ncbi.nlm.nih.gov
Colitis-associated cancer (CAC) is a relatively rare form of cancer with an unclear
pathogenesis. CAC serves as a prototype of inflammation associated cancers. Advanced …

A deep view of the biological property of interleukin-33 and its dysfunction in the gut

Y Wang, C He, S Xin, X Liu, S Zhang, B Qiao… - International Journal of …, 2023 - mdpi.com
Intestinal diseases have always posed a serious threat to human health, with inflammatory
bowel disease (IBD) being one of them. IBD is an autoimmune disease characterized by …

New sights of immunometabolism and agent progress in colitis associated colorectal cancer

J Zhang, C Chen, W Yan, Y Fu - Frontiers in Pharmacology, 2024 - frontiersin.org
Colitis associated colorectal cancer is a disease with a high incidence and complex course
that develops from chronic inflammation and deteriorates after various immune responses …

Rates and characteristics of postcolonoscopy colorectal cancer in the Swedish IBD population: what are the differences from a non-IBD population?

J Stjärngrim, A Ekbom, U Hammar, R Hultcrantz… - Gut, 2019 - gut.bmj.com
Objective The rate of postcolonoscopy colorectal cancer (PCCRC) is considered a key
quality indicator of colonoscopy; little is known about PCCRC in IBD. Design A population …

Inflammation in the proximal colon is a risk factor for the development of colorectal neoplasia in inflammatory bowel disease patients with primary sclerosing …

OK Jamil, D Shaw, Z Deng, N Dinardi… - Therapeutic …, 2023 - journals.sagepub.com
Background: Patients with primary sclerosing cholangitis (PSC) and inflammatory bowel
disease (IBD) have an increased risk of developing colorectal neoplasia (CRN) in the …

Organosulfur Compounds in Colorectal Cancer Prevention and Progression

PL McAlpine, J Fernández, CJ Villar, F Lombó - Nutrients, 2024 - mdpi.com
This work represents an overview of the current investigations involving organosulfur
compounds and colorectal cancer. The molecules discussed in this review have been …

Incidence and risk factors for preneoplastic and neoplastic lesions of the colon and rectum in patients under 50 referred for colonoscopy

S Agazzi, MV Lenti, C Klersy, E Strada, L Pozzi… - European journal of …, 2021 - Elsevier
Background: Colorectal cancer (CRC) diagnosed before the age of 50, known as early-
onset CRC (eoCRC), is considered uncommon. We aimed at analysing the incidence of …