New approaches to sepsis: molecular diagnostics and biomarkers

K Reinhart, M Bauer, NC Riedemann… - Clinical microbiology …, 2012 - Am Soc Microbiol
Sepsis is among the most common causes of death in hospitals. It arises from the host
response to infection. Currently, diagnosis relies on nonspecific physiological criteria and …

[HTML][HTML] The diagnostic accuracy of procalcitonin for bacteraemia: a systematic review and meta-analysis

SH Hoeboer, PJ van der Geest, D Nieboer… - Clinical Microbiology …, 2015 - Elsevier
The diagnostic use of procalcitonin for bacterial infections remains a matter of debate. Most
studies have used ambiguous outcome measures such as sepsis instead of infection. We …

Biomarkers of sepsis

JC Marshall, K Reinhart - Critical care medicine, 2009 - journals.lww.com
Background: A complex network of biological mediators underlies the clinical syndrome of
sepsis. The nonspecific physiologic criteria of sepsis syndrome or the systemic inflammatory …

Biomarkers for sepsis: A review with special attention to India

GE Nelson, V Mave, A Gupta - BioMed research international, 2014 - Wiley Online Library
Sepsis is a serious infection and still a common cause of morbidity and mortality in resource‐
limited settings such as India. Even when microbiologic diagnostics are available …

Predictive value of procalcitonin for excluding bloodstream infection: results of a retrospective study and utility of a rapid, quantitative test for procalcitonin

H Wang, F Yin, DX Shen, YJ Zhang… - Journal of …, 2013 - journals.sagepub.com
Objectives To assess retrospectively the diagnostic value of procalcitonin (PCT) in excluding
suspected bloodstream infection, establish cut-off values for PCT levels, and compare PCT …

History of biomarkers

M Roméo, L Giambérini… - … effects. CRC Press …, 2013 - api.taylorfrancis.com
Although knowledge of the existence of a link between biological dysfunction and the
environment is very old, as testified by writings dating from more than 2000 years ago …

A novel approach of platelet function test for prediction of attenuated response to clopidogrel

E Ezer, D Schrick, M Tőkés-Füzesi… - Clinical …, 2019 - content.iospress.com
BACKGROUND: Elevated mean platelet volume (MPV) and immature platelet fraction (IPF)
are predictive for vascular risk. Both can be associated with residual platelet reactivity. We …

Relationship between C-reactive protein and early activation of leukocytes indicated by leukocyte antisedimentation rate (LAR) in patients with acute cerebrovascular …

T Molnar, V Papp, M Banati, L Szereday… - Clinical …, 2010 - content.iospress.com
The purpose of this study was to determine the relationship between high-sensitive C-
reactive protein (hsCRP) and leukocyte antisedimentation rate (LAR) as a specific test to …

Human neutrophils swim and phagocytise bacteria

N Garcia‐Seyda, V Seveau, F Manca… - Biology of the …, 2021 - Wiley Online Library
Background Information Leukocytes migrate in an amoeboid fashion while patrolling our
organism in the search for infection or tissue damage. Their capacity to migrate has been …

Pediatric osteoarticular infection update

NI Montgomery, S Rosenfeld - Journal of Pediatric Orthopaedics, 2015 - journals.lww.com
Musculoskeletal infections are a common cause of morbidity in children. A multitude of
studies over the past few years have improved our knowledge and understanding of the …