Traumatic brain injury (TBI) and Alzheimer's disease (AD) are devastating neurological
disorders, whose complex relationship is not completely understood. Cerebrovascular …

Background The use of blood biomarkers after mild traumatic brain injury (mTBI) has been
widely studied. We have identified eight unresolved issues related to the use of five …

Axonal injury is a key determinant of long-term outcomes after traumatic brain injury (TBI) but
has been difficult to measure clinically. Fluid biomarker assays can now sensitively quantify …

Objective To determine whether neurofilament light (NfL), glial fibrillary acidic protein
(GFAP), tau, and ubiquitin C-terminal hydrolase-L1 (UCH-L1) measured in serum relate to …

Objective: To examine the effects of disease activity, disability, and disease-modifying
therapies (DMTs) on serum neurofilament light (NFL) and the correlation between NFL …

Objective To determine whether serum neurofilament light (NfL) correlates with CSF NfL,
traumatic brain injury (TBI) diagnosis, injury severity, brain volume, and diffusion tensor …

Objective To determine what tests and measures accurately diagnose persisting post-
concussive symptoms (PPCS) in children, adolescents and adults following sport-related …

Diagnostic and prognostic biomarkers for mild traumatic brain injury (TBI), also known as
concussion, remain a major unmet clinical need. Moderate to severe TBI can be diagnosed …

Objective To conduct a systematic review of published literature on advanced neuroimaging,
fluid biomarkers and genetic testing in the assessment of sport-related concussion (SRC) …

Objective To compare neurofilament light (NfL) and tau as blood-based biomarkers for acute
sports-related concussion (SRC) and determine whether their concentrations at different …