Alzheimer's disease (AD) is the most common cause of dementia, accounting for more than
50 million patients worldwide. Current evidence suggests the exact mechanism behind this …

Neuropsychiatric disorders and type 2 diabetes (T2D) are major public health concerns
proposed to be intimately connected. T2D is associated with increased risk of dementia …

Depression is a debilitating psychiatric ailment which exerts disastrous effects on one's
mental and physical health. Depression is accountable for augmentation of various life …

The gut microbiome is highly involved in numerous aspects of host physiology, from energy
harvest to stress response, and can confer many benefits to the host. The gut microbiome …

Close connections between depression and type 2 diabetes (T2DM) have been suggested
by many epidemiological and experimental studies. Disturbances in insulin sensitivity due to …

The broad beneficial effects of dietary polyphenols on human health have been confirmed.
Current studies have shown that dietary polyphenols are important for maintaining the …

Objective Antioxidants, chelating agents, and probiotics are used to manage the toxic effects
of cadmium (Cd) and mercury (Hg). The aim of this study was to investigate the combined …

Aims To assess protective efficacy of genetically modified Escherichia coli Nissle 1917 (Ec
N) on metabolic effects induced by chronic consumption of dietary fructose. Materials and …

According to the classic definition of aging we share, it is a combination of changes in an
organism leading to an increase in the probability of its death (rate of mortality). 1–4 It should …

Objective The objective of this study was to develop genetically modified probiotic E. coli
Nissle 1917 (EcN-23) slowly releasing 2-ketogluconic acid (2-KG) as a chelator and …