Despite tremendous efforts in the past two years, our understanding of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), virus–host interactions, immune …

Introduction The recent outbreak of SARS-CoV-2 has significantly increased the need to find
inhibitors that target the essential enzymes for viral replication in host cells. This systematic …

Background: In the last few years, in silico tools, including drug repurposing coupled with
structure-based virtual screening, have been extensively employed to look for anti-COVID …

The Zika virus (ZIKV) epidemic poses a significant threat to human health globally. Thus,
there is an urgent need for developing effective anti-ZIKV agents. ZIKV non-structural protein …

The coronavirus pandemic led to the announcement of a worldwide health emergency. The
SARS-CoV-2 Omicron variant, which swiftly spread worldwide, has fueled existing …

Highlights What are the main findings? Bioactive compounds of Moringa oleifera exhibited
activity against SARS-CoV-2. Computational approaches to studying the antiviral activity of …

Abstract A series of 1 ″-(alkylsulfonyl)-dispiro [indoline-3, 2′-pyrrolidine-3′, 3 ″-
piperidine]-2, 4 ″-diones 6a‒o has been synthesized through regioselective multi …

The COVID-19 outbreak and the pandemic situation have hastened the research community
to design a novel drug and vaccine against its causative organism, the SARS-CoV-2. The …

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), known to cause the
coronavirus disease 2019 (COVID-19), was declared a pandemic in early 2020. During the …

Virus infections and epidemics are becoming more common over the world, with new and
old viruses resurfacing with fresh intensity. As a result of long development phases, allergic …