Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …

In order to optimize a lead molecule for further development, bioisosteric replacements are
generally adopted as one of the strategies. Silicon appears to be the right choice as a …

The intense far-red absorption and emission features have made silicon phthalocyanines
(SiPcs) distinct from the structurally related porphyrin analogues. Unlike most other …

Bioisosterism is one of the leading strategies in medicinal chemistry for the design and
modification of drugs, consisting in replacing an atom or a substituent with a different atom or …

Abstract Although Sonophotodynamic Therapy (SPDT) studies, which are a new approach
that give better results than Photodynamic Therapy (PDT) in which light and sound are used …

Existing strategies that use tissue-penetrant near-infrared light for the targeted treatment of
cancer typically rely on the local generation of reactive oxygen species. This approach can …

In this paper we describe a straightforward supramolecular strategy to encapsulate silicon
phthalocyanine (SiPc) photosensitizers (PS) in polymeric micelles made of poly (ε …

Nanoparticles offer great opportunities for precision medicine. However, the use of
nanoparticles as smart photosensitizers that target tumor biomarkers and are responsive to …

Today, the problem of antimicrobial resistance is the most important cause of morbidity and
mortality in the treatment of infectious diseases worldwide. Therefore, alternative treatment …

Photoimmunotherapy (PIT) is a new molecular-targeted phototherapy in which
administration of an antibody conjugated to IR700 (Ab-IR700, a phthalocyanine derivative) …