Effective prevention and early diagnostic strategies are the most important public health
interventions in gastric cancer, which remains a common malignancy worldwide. Preventive …

Gastric cancer (GC) is one of the leading causes of cancer related death in the world,
particularly in East Asia. According to the Correa's cancer cascade, non-cardia GC is usually …

The prevalence of Helicobacter pylori infection in Indonesia is still controversial and mainly
investigated in the largest ethnic group, Javanese. We examined the prevalence of H. pylori …

Background: Defects in protein homeostasis are sufficient to provoke cardiac remodeling
and dysfunction. Although posttranslational modifications by ubiquitin and ubiquitin-like …

The ubiquitin-fold modifier 1 (Ufm1) is a posttranslational modifier that belongs to the
ubiquitin-like protein (UBL) family. Ufm1 is present in nearly all eukaryotic organisms, with …

Intestinal exocrine secretory cells, including Paneth and goblet cells, have a pivotal role in
intestinal barrier function and mucosal immunity. Dysfunction of these cells may lead to the …

The existence of any infectious agent in a highly acidic human stomach is contentious, but
the chance finding of Helicobacter pylori is by no means an accident. Once H. pylori …

The prevalence of Helicobacter pylori infection in Indonesia is controversial. We examined
the H. pylori infection rate in 78 patients in a hospital in Surabaya using five different tests …

Highlights•Current understanding of the Ufm1 conjugation system is discussed.•Ufmylation
genes have an essential role in the hematopoietic system.•A possible working mechanism …

Thrombospondin-2 (THBS2) and Thrombospondin-4 (THBS 4) play an important role in
cancer development and progression. However, genetic evidence for their roles in gastric …