Perilla frutescens (L.) Britton, an important pharmaceutical and nutraceutical crop, is widely
cultivated in East Asian countries. In this review, we present the latest research findings on …

Gout is characterized by hyperuricemia and the deposition of monosodium urate (MSU)
crystals around joints. Despite the availability of several drugs on the market, its treatment …

Purpose The present study investigates the phytosynthesis of silver nanoparticles (AgNPs)
using Perilla frutescens leaf extract, which acts as a reducing agent for the conversion of …

In this study, some flavonoids were screened as potent xanthine oxidase (XO) inhibitors in
vitro. Flavonoid 9 was demonstrated to exhibit the inhibitory activity through a ping-pong …

The present study was conducted to evaluate the influence of ultrasound on bioactive
compounds and biological activities of blue butterfly pea flower (Clitoria ternatea L.). For this …

Xanthine oxidase (XO) is a flavoprotein catalysing the oxidation of hypoxanthine to xanthine
and then to uric acid, while simultaneously producing reactive oxygen species. Altered …

Almost all drug molecules become the substrates for oxidoreductase enzymes, get
metabolized into more hydrophilic products and eliminated from the body. These …

Background Hyperuricemia is a state in which the serum levels of uric acid are elevated. As
such it has a pronounced effect on vascular and renal function with their consequences …

Xanthine oxidase (XO) has been well-recognized as a validated target for the treatment of
hyperuricemia and gout. Currently, there are two drugs in clinical use that shut down XO …

Barbituric and thiobarbituric acid derivatives have become progressively attractive to
medicinal chemists due to their wide range of biological activities. Herein, different series of …