Nrf2 signaling in coordinated activation of antioxidant gene expression

AK Jaiswal - Free Radical Biology and Medicine, 2004 - Elsevier
Antioxidant response element (ARE)-mediated expression and coordinated induction of
antioxidant enzymes is a critical mechanism of protection against chemically induced …

Integration and diversity of the regulatory network composed of Maf and CNC families of transcription factors

H Motohashi, T O'Connor, F Katsuoka, JD Engel… - Gene, 2002 - Elsevier
Recent progress in the analysis of transcriptional regulation has revealed the presence of an
exquisite functional network comprising the Maf and Cap'n'collar (CNC) families of …

Clinical and biologic implications of recurrent genomic aberrations in myeloma

R Fonseca, E Blood, M Rue, D Harrington, MM Oken… - Blood, 2003 - ashpublications.org
Nonrandom recurrent chromosomal abnormalities are ubiquitous in multiple myeloma (MM)
and include, among others, translocations of the immunoglobulin heavy chain locus (IgH) …

Distinct roles of Jun: Fos and Jun: ATF dimers in oncogenesis

H van Dam, M Castellazzi - Oncogene, 2001 - nature.com
Abstract Jun: Fos and Jun: ATF complexes represent two classes of AP-1 dimers that (1)
preferentially bind to either heptameric or octameric AP-1 binding sites, and (2) are …

The DF-1 chicken fibroblast cell line: transformation induced by diverse oncogenes and cell death resulting from infection by avian leukosis viruses

M Himly, DN Foster, I Bottoli, JS Iacovoni, PK Vogt - Virology, 1998 - Elsevier
DF-1 is a continuous cell line of chicken embryo fibroblasts. The cells are free of
endogenous sequences related to avian sarcoma and leukosis viruses and have normal …

Regulatory mechanisms of cellular response to oxidative stress

K Itoh, T Ishii, N Wakabayashi… - Free radical research, 1999 - Taylor & Francis
An antioxidant responsive element (ARE) or electrophile responsive element (EpRE)
mediates the transcriptional activation of genes encoding phase II drug metabolizing …

[HTML][HTML] The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4

IC Ho, MR Hodge, JW Rooney, LH Glimcher - Cell, 1996 - cell.com
The molecular basis for the distinctive cytokine expression of CD4+ T helper 1 (Th1) and T
helper 2 (Th2) subsets remains elusive. Here, we report that the proto-oncogene c-maf, a …

Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins

K Igarashi, K Kataokat, K Itoh, N Hayashi, M Nishizawa… - Nature, 1994 - nature.com
Abstract TRANSCRIPTION factor NF-E2 is crucial for regulating erythroid-specific gene
expression1. Cloning of the NF-E2 p45 protein has revealed that it contains a basic region …

Maf nuclear oncoprotein recognizes sequences related to an AP-1 site and forms heterodimers with both Fos and Jun

K Kataoka, M Noda, M Nishizawa - Molecular and cellular biology, 1994 - Taylor & Francis
The v-maf oncogene, identified from AS42 avian retrovirus, encodes a nuclear bZip protein.
To elucidate the molecular mechanism of cell transformation induced by this oncogene, we …

Frequent Dysregulation of the c-maf Proto-Oncogene at 16q23 by Translocation to an Ig Locus in Multiple Myeloma

M Chesi, PL Bergsagel, OO Shonukan… - Blood, The Journal …, 1998 - ashpublications.org
Dysregulation of oncogenes by translocation to an IgH (14q32) or IgL (κ, 2p11 or λ, 22q11)
locus is a frequent event in the pathogenesis of B-cell tumors. Translocations involving an …