Integrative metabolomics science in Alzheimer's disease: relevance and future perspectives

S Lista, R González-Domínguez, S López-Ortiz… - Ageing Research …, 2023 - Elsevier
Alzheimer's disease (AD) is determined by various pathophysiological mechanisms starting
10–25 years before the onset of clinical symptoms. As multiple functionally interconnected …

Plasmalogen in the brain: Effects on cognitive functions and behaviors attributable to its properties

J Udagawa, K Hino - Brain research bulletin, 2022 - Elsevier
Ether phospholipid compositions are altered in the plasma or brain of patients with brain
disorders, such as Alzheimer and Parkinson's disease, including those with psychiatric …

PFAS-induced lipidomic dysregulations and their associations with developmental toxicity in zebrafish embryos

Z Yang, L Fu, M Cao, F Li, J Li, Z Chen, A Guo… - Science of the Total …, 2023 - Elsevier
Per-and polyfluoroalkyl substances (PFASs) are persistent environmental contaminants,
posing developmental toxicity to fish and human. PFAS-induced lipid metabolism disorders …

An integrated study on the comprehensive mechanism of Schisandra chinensis polysaccharides mitigating Alzheimer's disease in rats using a UPLC-Q-TOF-MS …

J Fu, J Li, Y Sun, S Liu, F Song, Z Liu - Food & Function, 2023 - pubs.rsc.org
As a well-known traditional Chinese medicine and functional food, Schisandra chinensis (S.
chinensis) has been proved to possess excellent neuroprotective effects, and particularly the …

Marine fish-derived lysophosphatidylcholine: Properties, extraction, quantification, and brain health application

MK Ahmmed, M Hachem, F Ahmmed, A Rashidinejad… - Molecules, 2023 - mdpi.com
Long-chain omega-3 fatty acids esterified in lysophosphatidylcholine (LPC-omega-3) are
the most bioavailable omega-3 fatty acid form and are considered important for brain health …

Synthesis and application of mesoporous MIL-88A for enhanced lipase immobilization and high value oil conversion

Y Li, Z Liu, L Dai, D Liu, W Du - Chemical Engineering Journal, 2024 - Elsevier
Abstract MIL-88A, a metal–organic framework (MOF), has significant promise for lipase
immobilization due to its robust acid and water tolerance coupled with cost-effectiveness …

[HTML][HTML] Is fat the future for saving sight? Bioactive lipids and their impact on glaucoma

M Kolko, ZA Mouhammad, B Cvenkel - Pharmacology & Therapeutics, 2023 - Elsevier
Glaucoma is characterized by a continuous loss of retinal ganglion cells. The cause of
glaucoma is associated with an increase in intraocular pressure (IOP), but the underlying …

Phospholipidomics in clinical trials for brain disorders: advancing our understanding and therapeutic potentials

M Hachem, MK Ahmmed, H Nacir-Delord - Molecular Neurobiology, 2024 - Springer
Phospholipidomics is a specialized branch of lipidomics that focuses on the characterization
and quantification of phospholipids. By using sensitive analytical techniques …

Corylus avellana “Nocciola Piemonte”: metabolomics focused on polar lipids and phenolic compounds in fresh and roasted hazelnuts

A Cerulli, A Napolitano, B Olas, M Masullo… - Frontiers in Plant …, 2023 - frontiersin.org
The common hazel plant (Corylus avellana L., Betulaceae) is one of the most popular tree
nuts widespread in Europe and Asia. In Italy, there are different cultivars among which the …

Functional consequences of brain exposure to saturated fatty acids: From energy metabolism and insulin resistance to neuronal damage

K Sánchez‐Alegría, C Arias - Endocrinology, Diabetes & …, 2023 - Wiley Online Library
Abstract Introduction Saturated fatty acids (FAs) are the main component of high‐fat diets
(HFDs), and high consumption has been associated with the development of insulin …