Prion diseases are a group of rapidly progressive and always fatal neurodegenerative
disorders caused by misfolded prion protein in the brain. Although autopsy remains the gold …

CWD is an emergent prion disease that now affects cervid species on three continents. CWD
is efficiently spread in wild and captive populations, likely through both direct animal contact …

Transmissible spongiform encephalopathies (TSEs), or prions, are neurodegenerative
diseases that affect a variety of animal species, including humans. Cruetzfeldt–Jakob …

Abstract Real‐Time Quaking‐Induced Conversion (RT‐Qu IC) testing of human
cerebrospinal fluid (CSF) is highly sensitive and specific in discriminating sporadic CJD …

Efforts to contain the spread of chronic wasting disease (CWD), a fatal, contagious prion
disease of cervids, would be aided by the availability of additional diagnostic tools. RT-QuIC …

Chronic wasting disease (CWD) is a fatal prion disease of wild and captive cervids in North
America. Prions are infectious agents composed of a misfolded version of a host-encoded …

The minimum infectious dose required to induce CWD infection in cervids remains unknown,
as does whether peripherally shed prions and/or multiple low dose exposures are important …

Chronic wasting disease (CWD) is a prion disease circulating in wild and farmed cervid
populations throughout North America (United States and Canada), Europe (Finland …

Chronic wasting disease (CWD) affects cervids in North America, Asia, and Scandinavia.
CWD is unique in its efficient spread, partially because of contact with infectious prions shed …

Misfolded proteins associated with various neurodegenerative diseases often accumulate in
tissues or circulate in biological fluids years before the clinical onset, thus representing ideal …