Porosity is an important material feature commonly employed in implants and tissue
scaffolds. The presence of material voids permits the infiltration of cells, mechanical …

Over the last few decades, hot melt extrusion (HME) has emerged as a successful
technology for a broad spectrum of applications in the pharmaceutical industry. As indicated …

The main purpose of this work was to investigate the printability of different grades of
ethylene vinyl acetate (EVA) copolymers as new feedstock material for fused-deposition …

The goal of the present study was to fabricate drug-containing T-shaped prototypes of
intrauterine system (IUS) with the drug incorporated within the entire backbone of the …

The potential for use of polymers in controlled drug delivery systems has been long
recognized. Since their appearance in the literature, a wide range of degradable and non …

Melt extrusion (ME) over recent years has found widespread application as a viable drug
delivery option in the drug development process. ME applications include taste masking …

Highlights•We describe the principles of hot melt extrusion technology and its application in
drug delivery.•We highlight several, common biodegradable and nonbiodegradable …

Hot melt extrusion has been a widely used process in the pharmaceutical area for three
decades. In this field, it is important to optimize the formulation in order to meet specific …

Intraocular/Intravitreal implants constitute a relatively new method to treat eye diseases
successfully due to the possibility of releasing drugs in a controlled and prolonged way. This …

The purpose of this study was the in vitro and in vivo evaluation of the masking efficiency of
hot melt extruded paracetamol (PMOL) formulations. Extruded granules containing high …