Therapeutic targeting of the complement system: from rare diseases to pandemics
P Garred, AJ Tenner, TE Mollnes - Pharmacological reviews, 2021 - ASPET
The complement system was discovered at the end of the 19th century as a heat-labile
plasma component that “complemented” the antibodies in killing microbes, hence the name …
plasma component that “complemented” the antibodies in killing microbes, hence the name …
Eculizumab use in catastrophic antiphospholipid syndrome (CAPS): Descriptive analysis from the “CAPS Registry”
B López-Benjume, I Rodríguez-Pintó, MC Amigo… - Autoimmunity …, 2022 - Elsevier
Objectives To describe the real-world experience of eculizumab use in patients with
catastrophic antiphospholipid syndrome (CAPS) according to the information provided by …
catastrophic antiphospholipid syndrome (CAPS) according to the information provided by …
Guidelines on the Use of therapeutic apheresis in clinical practice–Evidence‐Based approach from the Writing Committee of the American Society for Apheresis: The …
L Connelly‐Smith, CR Alquist, NA Aqui… - Journal of clinical …, 2023 - Wiley Online Library
Abstract The American Society for Apheresis (ASFA) Journal of Clinical Apheresis (JCA)
Special Issue Writing Committee is charged with reviewing, updating, and categorizing …
Special Issue Writing Committee is charged with reviewing, updating, and categorizing …
Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients
JC Holter, SE Pischke, E de Boer… - Proceedings of the …, 2020 - National Acad Sciences
Respiratory failure in the acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
pandemic is hypothesized to be driven by an overreacting innate immune response, where …
pandemic is hypothesized to be driven by an overreacting innate immune response, where …
Guidelines on the use of therapeutic apheresis in clinical practice–evidence‐based approach from the Writing Committee of the American Society for Apheresis: the …
A Padmanabhan, L Connelly‐Smith… - Journal of clinical …, 2019 - Wiley Online Library
ABSTRACT The American Society for Apheresis (ASFA) Journal of Clinical Apheresis (JCA)
Special Issue Writing Committee is charged with reviewing, updating and categorizing …
Special Issue Writing Committee is charged with reviewing, updating and categorizing …
[HTML][HTML] Complement in secondary thrombotic microangiopathy
LMP Palma, M Sridharan, S Sethi - Kidney international reports, 2021 - Elsevier
Thrombotic microangiopathy (TMA) is a condition characterized by thrombocytopenia and
microangiopathic hemolytic anemia (MAHA) with varying degrees of organ damage in the …
microangiopathic hemolytic anemia (MAHA) with varying degrees of organ damage in the …
Complement in the pathophysiology of the antiphospholipid syndrome
The antiphospholipid syndrome (APS) is characterized by thrombosis and pregnancy
morbidity in the presence of antiphospholipid antibodies (aPL). Complement is a system of …
morbidity in the presence of antiphospholipid antibodies (aPL). Complement is a system of …
Complement, inflammation and thrombosis
E Rawish, M Sauter, R Sauter… - British Journal of …, 2021 - Wiley Online Library
A mutual relationship exists between immune activation and mechanisms of thrombus
formation. In particular, elements of the innate immune response such as the complement …
formation. In particular, elements of the innate immune response such as the complement …
The pathophysiology of the antiphospholipid syndrome: a perspective from the blood coagulation system
R Arreola-Diaz, A Majluf-Cruz… - Clinical and Applied …, 2022 - journals.sagepub.com
The antiphospholipid syndrome (APS), a systemic autoimmune disease characterized by a
hypercoagulability associated to vascular thrombosis and/or obstetric morbidity, is caused …
hypercoagulability associated to vascular thrombosis and/or obstetric morbidity, is caused …
Diagnosis and management of the antiphospholipid syndrome
S Chaturvedi, KR McCrae - Blood reviews, 2017 - Elsevier
Antiphospholipid syndrome (APS) is characterized by thrombosis and/or pregnancy
complications in the presence of persistent antiphospholipid antibodies (APLA). Laboratory …
complications in the presence of persistent antiphospholipid antibodies (APLA). Laboratory …