Treating menopause—MHT and beyond

SR Davis, RJ Baber - Nature Reviews Endocrinology, 2022 - nature.com
Every woman who lives past midlife will experience menopause, which, by definition, is
complete cessation of ovarian function. This process might occur spontaneously (natural …

Cachexia: A systemic consequence of progressive, unresolved disease

M Ferrer, TG Anthony, JS Ayres, G Biffi, JC Brown… - Cell, 2023 - cell.com
Cachexia, a systemic wasting condition, is considered a late consequence of diseases,
including cancer, organ failure, or infections, and contributes to significant morbidity and …

[HTML][HTML] Gene regulation by gonadal hormone receptors underlies brain sex differences

B Gegenhuber, MV Wu, R Bronstein, J Tollkuhn - Nature, 2022 - nature.com
Oestradiol establishes neural sex differences in many vertebrates 1, 2, 3 and modulates
mood, behaviour and energy balance in adulthood 4, 5, 6, 7, 8. In the canonical pathway …

Menopause: a cardiometabolic transition

RE Nappi, P Chedraui, I Lambrinoudaki… - The Lancet Diabetes & …, 2022 - thelancet.com
Menopause is often a turning point for women's health worldwide. Increasing knowledge
from experimental data and clinical studies indicates that cardiometabolic changes can …

[HTML][HTML] Estrogen as a key regulator of energy homeostasis and metabolic health

F Mahboobifard, MH Pourgholami, M Jorjani… - Biomedicine & …, 2022 - Elsevier
Over the last two decades, it has become evident that estrogens preserve the integrity of
energy homeostasis at central and peripheral levels. Estrogen deficiency, such as that …

Estradiol regulates leptin sensitivity to control feeding via hypothalamic Cited1

I González-García, E García-Clavé, A Cebrian-Serrano… - Cell metabolism, 2023 - cell.com
Until menopause, women have a lower propensity to develop metabolic diseases than men,
suggestive of a protective role for sex hormones. Although a functional synergy between …

[PDF][PDF] A functional cellular framework for sex and estrous cycle-dependent gene expression and behavior

JR Knoedler, S Inoue, DW Bayless, T Yang, A Tantry… - Cell, 2022 - cell.com
Sex hormones exert a profound influence on gendered behaviors. How individual sex
hormone-responsive neuronal populations regulate diverse sex-typical behaviors is unclear …

[图书][B] Experimental design and data analysis for biologists

GP Quinn, MJ Keough - 2002 - books.google.com
Publisher Description (unedited publisher data) An essential textbook for any student or
researcher in biology needing to design experiments, sampling programs or analyse the …

Hypothalamic control of innate social behaviors

L Mei, T Osakada, D Lin - Science, 2023 - science.org
Sexual, parental, and aggressive behaviors are central to the reproductive success of
individuals and species survival and thus are supported by hardwired neural circuits. The …

A maternal brain hormone that builds bone

ME Babey, WC Krause, K Chen, CB Herber, Z Torok… - Nature, 2024 - nature.com
In lactating mothers, the high calcium (Ca2+) demand for milk production triggers significant
bone loss. Although oestrogen normally counteracts excessive bone resorption by …