A comprehensive review of recent advances in the biological activities of quinazolines
HAM Gomaa - Chemical Biology & Drug Design, 2022 - Wiley Online Library
Quinazoline heterocycles are critical in the development of medications. Quinazoline
derivatives have been intensively researched, providing a wide range of compounds with …
derivatives have been intensively researched, providing a wide range of compounds with …
Quinazolinones, the winning horse in drug discovery
AM Alsibaee, HM Al-Yousef, HS Al-Salem - Molecules, 2023 - mdpi.com
Quinazolines are nitrogen-containing heterocycles that consist of a benzene ring fused with
a pyrimidine ring. Quinazolinones, oxidized quinazolines, are promising compounds with a …
a pyrimidine ring. Quinazolinones, oxidized quinazolines, are promising compounds with a …
Discovery of New Hydrazone-Thiazole Polyphenolic Antioxidants through Computer-Aided Design and In Vitro Experimental Validation
Oxidative stress is linked to a series of diseases; therefore, the development of efficient
antioxidants might be beneficial in preventing or ameliorating these conditions. Based on …
antioxidants might be beneficial in preventing or ameliorating these conditions. Based on …
Design, synthesis, molecular docking, biological evaluation, DFT and ADME studies of novel bisquinazolinone derivatives
Novel derivatives of bisquinazolinones and bisfuramides were synthesized and tested for
their efficiency in this work. Within short reaction times (1–10 min), bisfuramide derivatives …
their efficiency in this work. Within short reaction times (1–10 min), bisfuramide derivatives …
Antioxidant and Cytotoxic Activity of New Polyphenolic Derivatives of Quinazolin-4 (3H)-one: Synthesis and In Vitro Activities Evaluation
The development of hybrid molecules with significant human therapeutic properties is one of
the main approaches of pharmaceutical research. One of the most important …
the main approaches of pharmaceutical research. One of the most important …
Synthesis, In Vivo Anticonvulsant Activity Evaluation and In Silico Studies of Some Quinazolin-4 (3H)-One Derivatives
Two series,“a” and “b”, each consisting of nine chemical compounds, with 2, 3-disubstituted
quinazolin-4 (3H)-one scaffold, were synthesized and evaluated for their anticonvulsant …
quinazolin-4 (3H)-one scaffold, were synthesized and evaluated for their anticonvulsant …
[PDF][PDF] Fizes, an, I
The development of hybrid molecules with significant human therapeutic properties is one of
the main approaches of pharmaceutical research. One of the most important …
the main approaches of pharmaceutical research. One of the most important …
Antioxidant Activity Evaluation and Assessment of the Binding Affinity to HSA of a New Catechol Hydrazinyl-Thiazole Derivative
Polyphenols have attained pronounced attention due to their ability to provide numerous
health benefits and prevent several chronic diseases. In this study, we designed …
health benefits and prevent several chronic diseases. In this study, we designed …
Sinteza derivata kinazolinona u niskotemperaturnim eutektičkim otapalima primjenom odabranih metoda zelene kemije
M Komar - 2022 - repozitorij.fkit.unizg.hr
Sažetak U okviru doktorskog rada sintezirani su 2, 3-disupstituirani (1–130) i 3-supstituirani
derivati kinazolin-4 (3H)-ona (131–136) u niskotemperaturnim eutektičkim otapalima s …
derivati kinazolin-4 (3H)-ona (131–136) u niskotemperaturnim eutektičkim otapalima s …
Effect of Bridging Atom and Hydroxyl Position on the Antioxidant Capacity of Six Phenolic Schiff Bases
A series of new phenolic Schiff bases N, N-bis (2, 3-dihydroxybenzyl-idene)-4, 4'-
diphenylmethane (3-DPM), and N, N-bis (2, 5-dihydroxybenzylidene)-4, 4'-diphenylmethane …
diphenylmethane (3-DPM), and N, N-bis (2, 5-dihydroxybenzylidene)-4, 4'-diphenylmethane …