Protective effect of quercetin on kidney diseases: From chemistry to herbal medicines

YQ Chen, HY Chen, QQ Tang, YF Li, XS Liu… - Frontiers in …, 2022 - frontiersin.org
Kidney injuries may trigger renal fibrosis and lead to chronic kidney disease (CKD), but
effective therapeutic strategies are still limited. Quercetin is a natural flavonoid widely …

Effects of environmental and pathological hypoxia on male fertility

Z Li, S Wang, C Gong, Y Hu, J Liu, W Wang… - Frontiers in Cell and …, 2021 - frontiersin.org
Male infertility is a widespread health problem affecting approximately 6%–8% of the male
population, and hypoxia may be a causative factor. In mammals, two types of hypoxia are …

Mild magnetothermal enhanced nanocatalytic immunotherapy for solid tumors by immune cell activation and intratumoral infiltration

H Fu, L Chen, W Fang, P Hu, J Shi - Nano Today, 2023 - Elsevier
Immunotherapy is based on the systemic immunity activation against malignacies, which is
becoming one of the most promising modalities in solid tumor therapy. Unfortunately, the …

[PDF][PDF] Alleviative effects of combined topical melatonin and rutin on imiquimod-induced psoriasis mouse model

SM Khorsheed, AR Abu-Raghif… - Pharmacia, 2024 - pharmacia.pensoft.net
Background: Psoriasis is a longstanding autoimmune dermatosis with thickened, reddish-
brown, and flaking skin lesions. Melatonin is an indolamine hormone exhibiting antioxidant …

[HTML][HTML] Research progress of melatonin (MT) in improving ovarian function: a review of the current status

YM Guo, TC Sun, HP Wang, X Chen - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Melatonin (MT) is an endogenous hormone mainly synthesized by pineal cells, which has
strong endogenous effects of eliminating free radicals and resisting oxidative damages …

Quercetin antagonizes glucose fluctuation induced renal injury by inhibiting aerobic glycolysis via HIF-1α/miR-210/ISCU/FeS pathway

W Xu, S Liu, N Li, L Ye, M Zha, C Li, Y Zhao… - Frontiers in …, 2021 - frontiersin.org
Background and Objective: Glucose fluctuation (GF) has been reported to induce renal
injury and diabetic nephropathy (DN). However, the mechanism still remains ambiguous …

[PDF][PDF] Anti-proliferative, anti-oxidant and anti-inflammatory effects of topical rutin on imiquimod-induced psoriasis in mice

SM Khorsheed, ARA Raghif - Pak j life soc Sc, 2024 - pjlss.edu.pk
Psoriasis is a chronic autoimmune dermatosis characterized by thickened, reddish-brown,
and peeling skin lesions. To evaluate the potential Antiproliferative, Anti-oxidant and Anti …

Hypobaric hypoxia induced renal injury in rats: Prophylactic amelioration by quercetin supplementation

V Rathi, I Tiwari, R Kulshreshtha, S SK Sagi - Plos one, 2023 - journals.plos.org
The present study aims at assessing the effect of hypobaric hypoxia induced renal damage
and associated renal functions in male SD rats. Further, this study was extended to explore …

[HTML][HTML] Melatonin Alleviates Acute Respiratory Distress Syndrome by Inhibiting Alveolar Macrophage NLRP3 Inflammasomes Through the ROS/HIF-1α/GLUT1 …

L Zheng, W Zhou, Y Wu, W Xu, S Hu, Y Zhang… - Laboratory …, 2023 - Elsevier
Sepsis-induced acute respiratory distress syndrome (ARDS) is a devastating clinically
severe respiratory disorder, and no effective therapy is available. Melatonin (MEL), an …

[HTML][HTML] Inflammatory mediators-induced DNA damage in liver and brain injury: Therapeutic approach of 5-Methoy-N-acetyltryptamine

MO Kadry, HM Ali - Toxicology Reports, 2024 - Elsevier
The pathophysiology of hepatic and cerebral damage includes various molecular and
signalling pathways. Assessment of inflammation-induced DNA damage is one of the …