The autonomic nervous system in septic shock and its role as a future therapeutic target: a narrative review

M Carrara, M Ferrario, B Bollen Pinto, A Herpain - Annals of intensive care, 2021 - Springer
The autonomic nervous system (ANS) regulates the cardiovascular system. A growing body
of experimental and clinical evidence confirms significant dysfunction of this regulation …

Life in a dark biosphere: a review of circadian physiology in “arrhythmic” environments

AD Beale, D Whitmore, D Moran - Journal of Comparative Physiology B, 2016 - Springer
Most of the life with which humans interact is exposed to highly rhythmic and extremely
predictable changes in illumination that occur with the daily events of sunrise and sunset …

Stattic ameliorates the cecal ligation and puncture-induced cardiac injury in septic mice via IL-6-gp130-STAT3 signaling pathway

S Imbaby, Y Hattori - Life Sciences, 2023 - Elsevier
Aim Sepsis-induced cardiac dysfunction is the leading cause of higher morbidity and
mortality with poor prognosis in septic patients. Our recent previous investigation provides …

Abnormal heart rate characteristics before clinical diagnosis of necrotizing enterocolitis

ML Stone, PM Tatum, JH Weitkamp… - Journal of …, 2013 - nature.com
Objective: Earlier diagnosis and treatment of necrotizing enterocolitis (NEC) in preterm
infants, before clinical deterioration, might improve outcomes. A monitor that measures …

Sepsis-associated encephalopathy: a magnetic resonance imaging and spectroscopy study

FA Bozza, P Garteiser, MF Oliveira… - Journal of Cerebral …, 2010 - journals.sagepub.com
Brain dysfunction is frequently observed in sepsis as a consequence of changes in cerebral
structure and metabolism, resulting in worse outcome and reduced life-quality of surviving …

[HTML][HTML] Beta-blockers as an immunologic and autonomic manipulator in critically ill patients: a review of the recent literature

AM Eraky, Y Yerramalla, A Khan, Y Mokhtar… - International Journal of …, 2024 - mdpi.com
The autonomic nervous system plays a key role in maintaining body hemostasis through
both the sympathetic and parasympathetic nervous systems. Sympathetic overstimulation as …

Autonomic nervous system dysfunction in pediatric sepsis

CM Badke, LE Marsillio, DE Weese-Mayer… - Frontiers in …, 2018 - frontiersin.org
The autonomic nervous system (ANS) plays a major role in maintaining homeostasis
through key adaptive responses to stress, including severe infections and sepsis. The ANS …

Vasopressin and copeptin release during sepsis and septic shock

DA Gomes, RL de Almeida Beltrão… - Peptides, 2021 - Elsevier
Sepsis is defined as a potentially fatal organ dysfunction caused by a dysregulated host
response to infection. Despite tremendous progress in the medical sciences, sepsis remains …

Vasopressin and its immune effects in septic shock

JA Russell, KR Walley - Journal of innate immunity, 2010 - karger.com
Vasopressin is a stress hormone. However, vasopressin levels are inappropriately low in
septic shock. Vasopressin stimulates AVPR1a, AVPR1b, AVPR2 and purinergic receptors …

Adenosine, lidocaine, and Mg2+ (ALM): from cardiac surgery to combat casualty care—teaching old drugs new tricks

GP Dobson, HL Letson - Journal of Trauma and Acute Care …, 2016 - journals.lww.com
New frontline drugs and therapies are urgently required to protect the body from primary and
secondary injuries. We review more than 10 years of work on adenosine, lidocaine, and …