Accessing the natural genetic diversity of species unveils hidden genetic traits, clarifies gene functions and allows the generalizability of laboratory findings to be assessed. One notable …
JL Steenwyk, C Balamurugan, HA Raja… - Microbiology …, 2024 - Am Soc Microbiol
Modern taxonomic classification is often based on phylogenetic analyses of a few molecular markers, although single-gene studies are still common. Here, we leverage genome-scale …
Aspergillus fumigatus is both an environmental saprobe and an opportunistic human fungal pathogen. Knowledge of genomic variation across A. fumigatus isolates is essential for …
Many distantly related organisms have convergently evolved traits and lifestyles that enable them to live in similar ecological environments. However, the extent of phenotypic …
Molecular evolution studies, such as phylogenomic studies and genome-wide surveys of selection, often rely on gene families of single-copy orthologs (SC-OGs). Large gene …
B Yuan, MF Grau, RM Murata, T Torok… - ACS …, 2023 - ACS Publications
Filamentous fungi are an essential source of bioactive mycotoxins. Recent efforts have focused on developing antifungal agents that are effective against invasive yeasts, such as …
Multiple sequence alignments and phylogenetic trees are rich in biological information and are fundamental to research in biology. PhyKIT is a tool for processing and analyzing the …
JL Steenwyk, S Knowles, RW Bastos, C Balamurugan… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Cryptic fungal pathogens pose significant identification and disease management challenges due to their morphological resemblance to known pathogenic species while …
Asgardarchaeota, commonly referred to as Asgard archaea, are a candidatus phylum-level archaeal clade that includes the closest archaeal relatives of eukaryotes. Despite their …